Nexø E, Lamberg S I, Hollenberg M D
Scand J Clin Lab Invest. 1981 Oct;41(6):577-82. doi: 10.3109/00365518109090501.
A radioreceptor assay for human epidermal growth factor-urogastrone (EGF-URO) employing mouse EGF-URO as tracer and calibration standards and human placental receptor as binding protein is compared with a radioimmunoassay for human EGF-URO. Results employing the receptor assay indicated similar values for urinary concentrations (1-16 nmol/l) for healthy control subjects and for patients with psoriasis. Lower values were obtained for bed-ridden patients with burns or patients recovering from orthopaedic surgery. The results obtained by radioimmunoassay were somewhat higher and correlated poorly (r = 0.5) with those obtained with the radioreceptor assay. The reason for this discrepancy is discussed.
采用小鼠表皮生长因子-尿抑胃素（EGF-URO）作为示踪剂和校准标准品，以人胎盘受体作为结合蛋白，对人表皮生长因子-尿抑胃素（EGF-URO）进行放射受体分析，并与针对人EGF-URO的放射免疫分析进行比较。采用受体分析得到的结果表明，健康对照受试者和银屑病患者的尿浓度（1-16 nmol/l）值相似。卧床烧伤患者或骨科手术后恢复的患者得到的值较低。放射免疫分析得到的结果略高，且与放射受体分析得到的结果相关性较差（r = 0.5）。文中讨论了这种差异的原因。
