Akasu T, Koketsu K
Neurosci Lett. 1982 Mar 17;29(1):41-5. doi: 10.1016/0304-3940(82)90361-5.
The muscarinic actions of acetylcholine (ACh) on the action potentials of bullfrog sympathetic ganglion cells were studied with voltage-clamp experiments. The slow inward current (Isi) carried by Ca2+ was markedly depressed by ACh. ACh also markedly depressed the time-dependent outward current following Isi. The outward current was composed of two components, a TEA-sensitive rectifier K+ current (IK1) and a TEA-insensitive slow rectifier K+ current (IK2). Both of these components were depressed by ACh.
通过电压钳实验研究了乙酰胆碱（ACh）对牛蛙交感神经节细胞动作电位的毒蕈碱样作用。由Ca2+携带的缓慢内向电流（Isi）被ACh显著抑制。ACh还显著抑制了跟随Isi的时间依赖性外向电流。外向电流由两个成分组成，一个是四乙铵（TEA）敏感的整流钾电流（IK1）和一个TEA不敏感的缓慢整流钾电流（IK2）。这两个成分均被ACh抑制。
