Szadkowska D, Boroń P, Borzuchowska A, Prokopowicz D, Boroń-Kaczmarska A
Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1981 Dec;251(2):273-8.
The effect of Levamisol administered to patients with trichinosis, the influence thereof on the behaviour of lymphocytes T and B in the peripheral blood as well as the clinical course of the disease were analysed. In the 4th week Levamisol was administered to the patients in doses of 150 mg/24 h for 3 days and the same dose was given for 7 days in the 2nd and 4th week of the disease. The control group included patients with trichinosis who had not been given any drugs to produce immunological processes. A slight decrease in the percentage of T lymphocytes in the peripheral blood was observed in patients who had received Levamisol, immediately after having begun treatment. An increase in the percentage of T lymphocytes was noted in the patients who were treated with the drug as early as in the 2nd week of the disease. In patients treated with Levamisol, subjective complaints were observed which, however, ceased soon afterwards. No side effects of the drug were found.
分析了左旋咪唑对旋毛虫病患者的疗效、其对外周血中T和B淋巴细胞行为的影响以及疾病的临床进程。在第4周，以150mg/24h的剂量给患者服用左旋咪唑，持续3天，并在疾病的第2周和第4周以相同剂量给药7天。对照组包括未接受任何药物以产生免疫过程的旋毛虫病患者。接受左旋咪唑治疗的患者在开始治疗后外周血中T淋巴细胞百分比略有下降。早在疾病第2周接受该药物治疗的患者中，T淋巴细胞百分比有所增加。在接受左旋咪唑治疗的患者中观察到主观不适，但随后很快消失。未发现该药物的副作用。
