Lewensohn R, Ringborg U, Baral E, Lambert B
J Cell Sci. 1982 Apr;54:69-78. doi: 10.1242/jcs.54.1.69.
Human peripheral blood lymphocytes enriched in T or B cells were exposed to ultraviolet irradiation, nitrogen mustard or methylmethane sulphonate and investigated regarding their capacity for DNA repair synthesis. The DNA repair synthesis, measured as [3H] thymidine incorporated, was determined by autoradiography as unscheduled DNA synthesis (UDS). No systematic difference could be found in the capacity for UDS between the T- and B-cell-enriched fractions. A larger individual variation in UDS was found in the B-cell- compared to the T-cell-enriched lymphocytes.
将富含T细胞或B细胞的人外周血淋巴细胞暴露于紫外线照射、氮芥或甲基磺酸甲酯下，并研究其DNA修复合成能力。以掺入的[3H]胸腺嘧啶核苷来衡量的DNA修复合成，通过放射自显影法测定为非定标DNA合成（UDS）。在富含T细胞和富含B细胞的组分之间，未发现UDS能力存在系统性差异。与富含T细胞的淋巴细胞相比，在富含B细胞的淋巴细胞中发现UDS存在更大的个体差异。
