Epishin A V
Probl Endokrinol (Mosk). 1982 Mar-Apr;28(2):26-30.
Absolute and relative content of the peripheral blood T-, B- and "zero" cells was studied in 204 patients with thyroid pathology (154 subjects with toxic and 32 with non-toxic goiter, 12 with hypothyrosis and 6 with Hashimoto thyroiditis) by means of spontaneous and complementary rosette-forming method. Patients, suffering from thyroid diseases, mainly from moderate and severe goiter, hypothyrosis and Hashimoto goiter, developed changes in T- and B-lymphocyte system, manifesting in significant fall of the blood absolute and relative T-cell number and B-lymphocyte count increase. Frequency and extent of these alterations depend on severity of toxic goiter, ophthalmopathy and chronic infection presence. T- and B-lymphocyte system does not return to normal in the nearest periods after the drug treatment.
采用自发和互补性玫瑰花结形成法，对204例甲状腺疾病患者（154例毒性甲状腺肿、32例非毒性甲状腺肿、12例甲状腺功能减退症和6例桥本甲状腺炎患者）外周血T细胞、B细胞及“零”细胞的绝对和相对含量进行了研究。患有甲状腺疾病的患者，主要是中度和重度甲状腺肿、甲状腺功能减退症和桥本甲状腺肿患者，其T淋巴细胞和B淋巴细胞系统发生了变化，表现为血液中T细胞绝对数和相对数显著下降，B淋巴细胞计数增加。这些改变的频率和程度取决于毒性甲状腺肿的严重程度、眼病及慢性感染的存在情况。药物治疗后的近期内，T淋巴细胞和B淋巴细胞系统未恢复正常。
