使用经阳性选择的Lyt-2⁺小鼠脾细胞来检测针对同种异体抗原和经三硝基苯修饰的同基因细胞的反应中白细胞介素-2的分泌情况。 - Suppr

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Use of positively selected Lyt-2+ mouse splenocytes to examine interleukin-2 secretion in responses to alloantigens and to TNP-modified syngeneic cells.

作者信息

Miller R A, Stutman O

出版信息

Cell Immunol. 1982 Mar 15;68(1):114-27. doi: 10.1016/0008-8749(82)90094-6.

DOI:10.1016/0008-8749(82)90094-6

PMID:6979398

Abstract

摘要

相似文献

Use of positively selected Lyt-2+ mouse splenocytes to examine interleukin-2 secretion in responses to alloantigens and to TNP-modified syngeneic cells.使用经阳性选择的Lyt-2⁺小鼠脾细胞来检测针对同种异体抗原和经三硝基苯修饰的同基因细胞的反应中白细胞介素-2的分泌情况。

Cell Immunol. 1982 Mar 15;68(1):114-27. doi: 10.1016/0008-8749(82)90094-6.

T-cell responses induced by the parenteral injection of antigen-modified syngeneic cells. II. Mechanisms, specificity, and cellular analysis of 2,4,6-trinitrophenol (TNP)-specific cytolytic response priming by intravenous versus subcutaneous injection with TNP-modified syngeneic cells.经肠胃外注射抗原修饰的同基因细胞诱导的T细胞应答。II. 通过静脉注射与皮下注射三硝基苯酚（TNP）修饰的同基因细胞引发TNP特异性溶细胞应答的机制、特异性及细胞分析

Cell Immunol. 1983 Dec;82(2):378-93. doi: 10.1016/0008-8749(83)90171-5.

Decline, in aging mice, of the anti-2,4,6-trinitrophenyl (TNP) cytotoxic T cell response attributable to loss of Lyt-2-, interleukin 2-producing helper cell function.衰老小鼠中，抗2,4,6-三硝基苯基（TNP）细胞毒性T细胞反应的下降归因于Lyt-2+、产生白细胞介素2的辅助细胞功能的丧失。

Eur J Immunol. 1981 Oct;11(10):751-6. doi: 10.1002/eji.1830111004.

Generation of cytotoxic T lymphocytes against TNP-haptenated syngeneic cells in microcultures: the effect of nude spleen cells as accessory cells.

Cell Immunol. 1981 Aug;62(2):385-95. doi: 10.1016/0008-8749(81)90339-7.

The cytolytic T lymphocyte response to trinitrophenyl-modified syngeneic cells. I. Evidence for antigen-specific helper T cells.细胞溶解性T淋巴细胞对三硝基苯修饰的同基因细胞的反应。I. 抗原特异性辅助性T细胞的证据。

J Immunol. 1979 Sep;123(3):1205-9.

Genetic control of cytolytic t-lymphocyte responses. II. The role of the host genotype in parental leads to F1 radiation chimeras in the control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells.细胞溶解型T淋巴细胞反应的遗传控制。II. 宿主基因型在亲代导致F1辐射嵌合体中对三硝基苯修饰的同基因细胞的细胞溶解型T淋巴细胞反应特异性控制中的作用。

J Exp Med. 1978 Aug 1;148(2):352-9. doi: 10.1084/jem.148.2.352.

The use of a clonal assay for cytotoxic T lymphocytes to determine the Ly phenotypes of the cytotoxic precursor and effector cells to alloantigens and trinitrophenyl-modified self antigens.使用细胞毒性T淋巴细胞的克隆分析来确定细胞毒性前体细胞和效应细胞针对同种异体抗原和三硝基苯基修饰的自身抗原的Ly表型。

J Immunol. 1980 Nov;125(5):1977-86.

Genetic control of cell-mediated lympholysis to trinitrophenyl (TNP)-modified murine syngeneic cells. I. Expression of Ir gene function at the Cytotoxic precursor and helper cell levels in the response to TNP-H-2 b self.对三硝基苯基（TNP）修饰的小鼠同基因细胞的细胞介导淋巴细胞溶解的遗传控制。I. 在对TNP-H-2b自身反应中，Ir基因功能在细胞毒性前体细胞和辅助细胞水平的表达。

J Immunol. 1981 Mar;126(3):1047-51.

Delayed-type hypersensitivity induced in immunodeficient mice with syngeneic modified self antigens: a suggestive model of autoimmune response.用同基因修饰自身抗原在免疫缺陷小鼠中诱导的迟发型超敏反应：一种自身免疫反应的提示模型。

Eur J Immunol. 1982 Nov;12(11):961-6. doi: 10.1002/eji.1830121112.

Expression of both I-A and I-E/C subregion antigens on accessory cells required for in vitro generation of cytotoxic T lymphocytes against alloantigens or TNBS-modified syngeneic cells.在体外产生针对同种异体抗原或经三硝基苯磺酸修饰的同基因细胞的细胞毒性T淋巴细胞所需的辅助细胞上，I-A和I-E/C亚区抗原均有表达。

J Immunol. 1980 Apr;124(4):1911-6.

引用本文的文献

Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony-stimulating factor on the basis of Lyt-2 phenotype.分泌淋巴因子的同种异体反应性T淋巴细胞的前体频率分析。基于Lyt-2表型对产生白细胞介素2、巨噬细胞激活因子和粒细胞巨噬细胞集落刺激因子的亚群进行分离。

J Exp Med. 1982 Nov 1;156(5):1366-79. doi: 10.1084/jem.156.5.1366.

Influence of activating stimulus on functional phenotype: interleukin 2 mRNA accumulation differentially induced by ionophore and receptor ligands in subsets of murine T cells.激活刺激对功能表型的影响：离子载体和受体配体在小鼠T细胞亚群中差异诱导白细胞介素2 mRNA积累。

Proc Natl Acad Sci U S A. 1988 Sep;85(17):6503-7. doi: 10.1073/pnas.85.17.6503.

Regulation of herpes simplex virus-specific lymphoproliferation by suppressor cells.抑制细胞对单纯疱疹病毒特异性淋巴细胞增殖的调节

J Virol. 1985 Oct;56(1):1-6. doi: 10.1128/JVI.56.1.1-6.1985.

The autonomy of CD8+ T cells in vitro and in vivo.CD8 + T细胞在体外和体内的自主性。

Immunology. 1988 Oct;65(2):249-57.

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