[Dynamics of immunoregulator T-lymphocytes and its importance in the chemo-immunotherapy of lymphoproliferative diseases in children].

The levels of T-lymphocytes in untreated lymphoid malignancies in children and those after different schemes of chemoimmunotherapy were compared. The ratio of T-helper and T-suppressor cells changed in the course of treatment in correlation with the chemotherapeutic effect: the fraction of T mu cells practically did not change whereas the T gamma cell fraction decreased considerably in patients who revealed a good response to therapy. BCG treatment stimulated both populations but the response of T gamma cells was stronger. Transplantation of thymus was followed by an increase on T mu cells.