神经氨酸酶处理的绵羊红细胞玫瑰花结试验与淋巴增生性疾病患者淋巴细胞酸性磷酸酶活性之间的相关性。
Correlation between the rosette test with neuraminidase-treated sheep red blood cells and acid phosphatase activity in lymphocytes from patients with lymphoproliferative disease.
作者信息
Rudzka E, Hołowiecki J, Stella-Hołowiecka B, Krawczyk M
出版信息
Arch Immunol Ther Exp (Warsz). 1979;27(1-2):223-7.
In 14 adult patients suffering from lymphoproliferative diseases, the relation between numbers of lymphocytes determined by the rosette test (nSE) with neuraminidase-treated sheep red blood cells and numbers of lymphocytes giving a positive reaction for acid phosphatase was determined. Statistical analysis of multiple test results in the patients (n = 38) showed highly positive correlation between the two markers. A similar positive correlation in the course of cytostatic treatment was observed in selected patients with type T and B cell lymphoma. The results indicate that determination of acid phosphatase activity can serve as an additional marker of T lymphocytes in groups of patients with lymphoproliferative disease.
在14例患有淋巴增生性疾病的成年患者中，测定了用神经氨酸酶处理的绵羊红细胞通过玫瑰花结试验（nSE）所确定的淋巴细胞数量与对酸性磷酸酶呈阳性反应的淋巴细胞数量之间的关系。对这些患者（n = 38）的多项检测结果进行统计分析显示，这两种标志物之间存在高度正相关。在选定的T型和B型细胞淋巴瘤患者中，观察到在细胞抑制治疗过程中也有类似的正相关。结果表明，在淋巴增生性疾病患者群体中，酸性磷酸酶活性的测定可作为T淋巴细胞的一种附加标志物。
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