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9,3"-二乙酰麦迪霉素治疗小儿呼吸道感染的临床研究(作者译)

[Clinical studies on 9,3"-diacetylmidecamycin in respiratory tract infections in pediatric field (author's transl)].

作者信息

Aoyama R, Kakizaki Y, Ohnishi A, Izumi Y, Fujita M, Nagata K

出版信息

Jpn J Antibiot. 1982 Apr;35(4):919-22.

PMID:6980296
Abstract

Clinical studies on 9,3"-diacetylmidecamycin (MOM) was carried out in 31 patients with respiratory tract infections (acute pharyngitis 6, acute purulent tonsillitis 5, scarlet fever 1, acute bronchitis 6, pneumonia 13 cases), in dose of 12 approximately 34 mg/kg divided 3 per day for 3 approximately 19 days. The overally efficacy rate was 74.2%. As to adverse reaction, exanthema and diarrhea with abdominal pain were observed in each 1 patient. Eosinophilia and elevation of serum GPT were noted in each 1 patient.

摘要

对9,3"-二乙酰麦迪霉素(MOM)进行了临床研究,研究对象为31例呼吸道感染患者(急性咽炎6例、急性化脓性扁桃体炎5例、猩红热1例、急性支气管炎6例、肺炎13例),剂量为12至34毫克/千克,每日分3次服用,疗程为3至19天。总有效率为74.2%。不良反应方面,各有1例患者出现皮疹、伴有腹痛的腹泻。各有1例患者出现嗜酸性粒细胞增多和血清谷丙转氨酶升高。

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