Salti I S, Hajj H, Dhib-Jalbut S
J Steroid Biochem. 1982 Aug;17(2):155-7. doi: 10.1016/0022-4731(82)90115-7.
Incubations of [3H]-progesterone with testicular tissue obtained from a new case of male with 17 alpha-hydroxylase deficiency were performed. The per cent conversion to androstenedione and testosterone was virtually absent when compared to that obtained from an identical incubation performed using testicular tissue from a normal male with cryptochordism. The findings provide an in vitro evidence in support of the existence of 17 alpha-hydroxylase testicular defect in this disorder.
