Goodale R L, Silvis S E, O'Leary J F, Gebhard R, Mjollness L, Johnson M, Fryd D
Surg Gynecol Obstet. 1982 Oct;155(4):523-8.
Forty-two patients from the University of Minnesota Hospitals and Minneapolis Veterans Administration Hospital underwent sclerotherapy for endoscopically verified esophageal varices. No patient was excluded because of poor hepatic functional reserve or serious co-morbid condition. Eleven patients were actively bleeding at the time of sclerotherapy. Thirty-one were listed as Child class B and C. After sclerotherapy, six of 25 survivors have had obliteration of varices. Substantial improvement was noted endoscopically in eight others. The most frequent complication was rebleeding, which occurred in 20 patients. Rebleeding led to surgical intervention in seven and to seven nonoperative deaths. There were two instances of mesenteric venous thrombosis complication not previously described following sclerotherapy. Twenty-nine patients survived two months, and 16 patients are alive at six months. These figures compare quite favorably with survival figures from other groups of patients who had roughly comparable liver impairment and who underwent medical treatment or portacaval shunts as an emergency measure.
来自明尼苏达大学医院和明尼阿波利斯退伍军人管理局医院的42名患者接受了内镜证实的食管静脉曲张硬化治疗。没有患者因肝功能储备差或严重合并症而被排除。11名患者在硬化治疗时正在积极出血。31名患者被列为Child B级和C级。硬化治疗后，25名幸存者中有6名静脉曲张消失。内镜检查发现另外8名患者有明显改善。最常见的并发症是再出血，20名患者发生了再出血。再出血导致7名患者接受手术干预，7名患者非手术死亡。有2例肠系膜静脉血栓形成并发症，此前硬化治疗后未描述过。29名患者存活了两个月，16名患者在六个月时仍存活。这些数字与其他有大致相当肝功能损害且作为紧急措施接受药物治疗或门腔分流术的患者组的存活数字相比相当有利。
