5-氟尿嘧啶联合高剂量亚叶酸钙治疗晚期结直肠癌和胃腺癌：一项初步研究。 - Suppr

Treatment of advanced colorectal and gastric adenocarcinomas with 5-FU combined with high-dose folinic acid: a pilot study.

作者信息

Machover D, Schwarzenberg L, Goldschmidt E, Tourani J M, Michalski B, Hayat M, Dorval T, Misset J L, Jasmin C, Maral R, Mathé G

出版信息

Cancer Treat Rep. 1982 Oct;66(10):1803-7.

PMID:6982099

Abstract

摘要

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Treatment of advanced colorectal and gastric adenocarcinomas with 5-FU combined with high-dose folinic acid: a pilot study.5-氟尿嘧啶联合高剂量亚叶酸钙治疗晚期结直肠癌和胃腺癌：一项初步研究。

Cancer Treat Rep. 1982 Oct;66(10):1803-7.

[Treatment of rectocolic and gastric adenocarcinomas with 5-fluorouracil associated with high doses of folinic acid. Results of an experimental study].

Sem Hop. 1982 Sep 16;58(33):1873-5.

[Treatment of advanced colonic and rectal adenocarcinoma: combination of 5-FU and high-dose folinic acid].

Bull Cancer. 1983;70(5):434-6.

[Results of treatment with 5-fluorouracil and folinic acid in patients with carcinoma of the large intestine].[5-氟尿嘧啶与亚叶酸联合治疗大肠癌患者的疗效]

Medicina (Firenze). 1988 Apr-Jun;8(2):175-8.

Randomized comparison of melphalan and 5-fluorouracil in the treatment of advanced gastrointestinal cancer.

Cancer Treat Rep. 1976 Sep;60(9):1267-71.

Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid.用5-氟尿嘧啶和高剂量亚叶酸治疗晚期结直肠癌和胃腺癌。

J Clin Oncol. 1986 May;4(5):685-96. doi: 10.1200/JCO.1986.4.5.685.

Importance of 5-fluorouracil dose-intensity in a double randomised trial on adjuvant portal and systemic chemotherapy for Dukes B2 and C colorectal cancer.5-氟尿嘧啶剂量强度在一项针对Dukes B2和C期结直肠癌辅助门静脉及全身化疗的双随机试验中的重要性

Anticancer Res. 2000 Nov-Dec;20(6C):4665-72.

A pilot study of oxaliplatin, fluorouracil and folinic acid (FOLFOX-6) as first-line chemotherapy in advanced or recurrent gastric cancer.一项关于奥沙利铂、氟尿嘧啶和亚叶酸（FOLFOX-6）作为晚期或复发性胃癌一线化疗方案的试点研究。

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Ineffectiveness of sequential high dose methotrexate and 5-fluorouracil combined with epirubicin (FEMTX regimen) as a salvage therapy in advanced colorectal cancers and other gastrointestinal tumors.序贯大剂量甲氨蝶呤和5-氟尿嘧啶联合表柔比星（FEMTX方案）作为晚期结直肠癌和其他胃肠道肿瘤挽救治疗的无效性。

Anticancer Res. 1996 Jul-Aug;16(4A):2063-7.

Therapy of advanced gastrointestinal cancer with the nitrosoureas.亚硝基脲类药物治疗晚期胃肠道癌

Cancer Chemother Rep 3. 1973 May;4(3):27-34.

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Treatment of patients with carcinomas in advanced stages with 5-fluorouracil, folinic acid and pyridoxine in tandem.联合应用氟尿嘧啶、亚叶酸和吡哆醇治疗晚期癌患者。

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Colorectal Cancer: Disease Process, Current Treatment Options, and Future Perspectives.结直肠癌：疾病进程、当前治疗选择及未来展望

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Oral Tegafur-Uracil Combination plus Leucovorin versus Other Fluoropyrimidine Agents in Colorectal Cancer: A Systematic Review and Meta-Analysis.口服替加氟-尿嘧啶联合亚叶酸钙与其他氟嘧啶类药物治疗结直肠癌的系统评价和Meta分析

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Sci Rep. 2022 May 31;12(1):9079. doi: 10.1038/s41598-022-12998-5.

Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells.5-氟尿嘧啶耐药结直肠癌细胞中 KRAB 锌指蛋白的下调。

BMC Cancer. 2022 Apr 4;22(1):363. doi: 10.1186/s12885-022-09417-3.

Pharmacologic modulation of 5-fluorouracil by folinic acid and high-dose pyridoxine for treatment of patients with digestive tract carcinomas.亚叶酸和大剂量吡哆醇对 5-氟尿嘧啶的药物调节用于治疗消化道癌患者。

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A pharmacokinetic and pharmacodynamic investigation of Modufolin® compared to Isovorin® after single dose intravenous administration to patients with colon cancer: a randomized study.对结肠癌患者单次静脉给药后，Modufolin®与Isovorin®的药代动力学和药效学研究：一项随机研究。

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New insights into the role of age and carcinoembryonic antigen in the prognosis of colorectal cancer.年龄和癌胚抗原在结直肠癌预后中作用的新见解。

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Treatment of advanced colorectal and gastric adenocarcinomas with 5-FU combined with high-dose folinic acid: a pilot study.

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