Merienne L, Mazars G
Neurochirurgie. 1982;28(3):201-6.
Abnormal movements or dyskinesias are associated with hyperpathia and hyperalgesia in a number of conditions such as post amputation jumping stumps pseudothalamic syndromes following cerebro vascular accidents and in some cases of demyelinating diseases. Intermittent electrical stimulation of the specific sensory nucleus of the thalamus (I.T.S.) controls at the same time pain and dyskinesias with the same long lasting effect. In some cases where dyskinesias are associated with sensory deafferentation, but not with chronic pain or hyperpathia, the same positive effect of thalamic stimulation on the control of abnormal movements is achieved while in other cases of tremor or dyskinesias without sensory deafferentation such as parkinsonism, intention tremor etc.. the efficacy of I.T.S. is nil. Hence, discriminative sensory deaffrentation is the common link between the cases of tremor or dyskinesias that use to respond to I.T.S. which is up to now the only therapy of proven efficacy in such conditions.
异常运动或运动障碍与痛觉过敏和痛觉超敏相关,见于多种情况,如截肢后跳痛残端、脑血管意外后的假性丘脑综合征以及某些脱髓鞘疾病病例。间歇性电刺激丘脑特定感觉核(I.T.S.)可同时控制疼痛和运动障碍,且效果持久。在某些运动障碍与感觉传入阻滞相关,但与慢性疼痛或痛觉过敏无关的情况下,丘脑刺激对控制异常运动具有相同的积极效果,而在其他无感觉传入阻滞的震颤或运动障碍病例中,如帕金森病、意向性震颤等,I.T.S.无效。因此,有鉴别性的感觉传入阻滞是过去对I.T.S.有反应的震颤或运动障碍病例之间的共同联系,而I.T.S.是目前在这些情况下唯一经证实有效的治疗方法。