Marak G E, Rao N A, Antonakou G, Sliwinski A
Ophthalmic Res. 1982;14(4):292-7. doi: 10.1159/000265205.
Guinea pigs and mice after immunization with lens proteins were observed to develop a typical form of experimental phacoanaphylactic endophthalmitis after lens injury. Sensitization to lens protein elicited a good antibody response in rabbits, however no disease developed after lens injury. This is another example of frequent discrepancies between autoimmune responses and autoimmune disease and indicates the importance of investigating mechanisms of phlogogenicity in autoimmune disease.
用晶状体蛋白免疫后的豚鼠和小鼠,在晶状体损伤后被观察到发生典型形式的实验性晶状体过敏性眼内炎。对晶状体蛋白的致敏在兔中引发了良好的抗体反应,然而在晶状体损伤后未发生疾病。这是自身免疫反应和自身免疫性疾病之间频繁出现差异的另一个例子,并表明研究自身免疫性疾病中炎症发生机制的重要性。