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[实验性自身免疫状态下不同基因型小鼠T淋巴细胞和B淋巴细胞的腺苷酸环化酶含量]

[Adenylate cyclase content of T- and B-lymphocytes of mice of different genotypes in an experimental autoimmune state].

作者信息

Robinson M V, Shurlygina A V, Trufakin V A

出版信息

Tsitologiia. 1982 Jul;24(7):829-32.

PMID:6982548
Abstract

The activity of adenylcyclase in T and B cells of lymph nodes and spleen has been investigated in intact and autoimmune mice Balb/c and C57B1. Strain differences in the enzyme activity of intact and autoimmune mice were observed. It is concluded that the determination of adenylcyclase activity in lymphoid cells makes it possible to reveal the peculiarities of cell maturation in normal and pathological mice of different strains.

摘要

对正常和自身免疫的Balb/c及C57B1小鼠的淋巴结和脾脏中T细胞和B细胞的腺苷酸环化酶活性进行了研究。观察到正常和自身免疫小鼠在该酶活性方面存在品系差异。得出的结论是,测定淋巴细胞中的腺苷酸环化酶活性能够揭示不同品系正常和病理小鼠细胞成熟的特点。

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