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青蛙神经组织的神经节苷脂模式

Ganglioside patterns of frog nervous tissues.

作者信息

Ohashi M

出版信息

Adv Exp Med Biol. 1982;152:83-91.

PMID:6982604
Abstract

Frog gangliosides were prepared from the brain and the peripheral nerves and investigated by neuraminidase treatment. The precise distribution patterns of the total gangliosides and their hydrolysis products were analyzed by multiple two-dimensional thin-layer chromatography. It was found that frog nervous tissues contained unique gangliosides which were easily hydrolyzed by neuraminidase and converted into asialo-GM1, suggesting the presence of new linkages of the sialic acids.

摘要

从青蛙的脑和外周神经中制备神经节苷脂,并通过神经氨酸酶处理进行研究。通过多次二维薄层色谱分析了总神经节苷脂及其水解产物的精确分布模式。发现青蛙神经组织含有独特的神经节苷脂,这些神经节苷脂很容易被神经氨酸酶水解并转化为去唾液酸GM1,这表明存在唾液酸的新连接方式。

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