Jordan P, Unrau G O, Bartholomew R K, Cook J A, Grist E
Bull World Health Organ. 1982;60(4):583-8.
Between 1970 and 1975, the incidence of new Schistosoma mansoni infections was reduced in 5 villages after each household was provided with its individual water supply and community laundry shower units were made available. In 1975, 1976, and 1977 chemotherapy with oxamniquine was offered to persons found to be infected. Transmission was reduced further and remained at a low level for the next 4 years, with no sign of an increase in spite of the reservoir of infection remaining after therapy and a poor level of sanitation in the villages.Thus, properly maintained water supplies appear to be effective in maintaining transmission at a low level during the maintenance phase of a schistosomiasis control programme, after chemotherapy. Sporadic new infections must be anticipated among children, but these will probably be of low intensity and associated with minimal morbidity.
1970年至1975年间,在为每户提供独立供水并设置社区洗衣淋浴设施后,5个村庄的曼氏血吸虫新感染发病率有所降低。1975年、1976年和1977年,对检测出感染的人群使用羟氨喹进行化疗。传播率进一步降低,并在接下来的4年里维持在低水平,尽管治疗后仍有感染源且村庄卫生条件较差,但传播率并无上升迹象。因此,在血吸虫病控制项目的维持阶段,化疗后妥善维护的供水似乎能有效地将传播率维持在低水平。预计儿童中会出现零星的新感染病例,但这些感染可能强度较低且发病率极低。