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高危患者内镜下注射治疗止血

Endoscopic haemostasis by injection-therapy in high-risk patients.

作者信息

Wördehoff D, Gros H

出版信息

Endoscopy. 1982 Nov;14(6):196-9. doi: 10.1055/s-2007-1021620.

DOI:10.1055/s-2007-1021620
PMID:6982813
Abstract

The diagnosis of an upper gastrointestinal bleeding can be clarified quickly and reliably by emergency endoscopy. It would seem reasonable to make this efficient diagnostic approach available for therapy in order to stop the bleeding. Over a period of 2 1/2 years, we discovered an active bleeding or several recurrences during emergency endoscopy in 36 patients with a high operative risk. In these cases we attempted local haemostasis by sclerosing injections. Most patients had signs of shock at the time of admission. The average haemoglobin level was 7:42 g/100 ml, the average blood requirement was 4,4 units in the first 24 hours. 12 patients had stress lesions, 19 patients important factors militating against an operation, namely age and serious primary diseases, 5 patients had other risk factors. In 33 out of 36 patients (91.9%) haemostasis was accomplished during endoscopy. In 7 patients recurrences occurred, 3 bleeds were arrested by a repeated sclerosing. Thus definitive haemostasis was achieved in 29 patients (80.6%). We believe that it is justified to attempt endoscopic sclerotherapy in high-risk patients before undertaking an emergency operation.

摘要

通过急诊内镜检查能够迅速且可靠地明确上消化道出血的诊断。为了止血,使这种高效的诊断方法应用于治疗似乎是合理的。在2年半的时间里,我们在36例手术风险高的患者的急诊内镜检查中发现了活动性出血或多次复发。在这些病例中,我们尝试通过硬化剂注射进行局部止血。大多数患者入院时都有休克体征。平均血红蛋白水平为7.42g/100ml,最初24小时的平均输血量为4.4单位。12例患者有应激性病变,19例患者有不利于手术的重要因素,即年龄和严重的原发性疾病,5例患者有其他危险因素。36例患者中有33例(91.9%)在内镜检查期间实现了止血。7例患者出现复发,3例出血通过再次硬化剂注射得以止住。因此,29例患者(80.6%)实现了确定性止血。我们认为,在进行急诊手术之前,对高危患者尝试内镜硬化治疗是合理的。

相似文献

1
Endoscopic haemostasis by injection-therapy in high-risk patients.高危患者内镜下注射治疗止血
Endoscopy. 1982 Nov;14(6):196-9. doi: 10.1055/s-2007-1021620.
2
Endoscopic hemostasis by injection therapy and electro-hydro-coagulation in high-risk patients with active gastroduodenal bleeding ulcer.内镜下注射治疗和电水凝治疗对胃十二指肠活动性出血溃疡高危患者的止血作用
Endoscopy. 1987 Nov;19(6):225-7. doi: 10.1055/s-2007-1018289.
3
The benefits of endoscopy in upper gastrointestinal bleeding.内镜检查在上消化道出血中的益处。
Endoscopy. 1986 May;18 Suppl 2:15-7. doi: 10.1055/s-2007-1018420.
4
Results of emergency gastroscopy for acute upper gastrointestinal bleeding outside official hours at King Chulalongkorn Memorial Hospital.朱拉隆功国王纪念医院非工作时间急性上消化道出血的急诊胃镜检查结果
J Med Assoc Thai. 2003 Jun;86 Suppl 2:S465-71.
5
[Combined injection/endoscopic sclerotherapy of upper gastrointestinal peptic ulcer hemorrhage].[上消化道消化性溃疡出血的联合注射/内镜硬化治疗]
Orv Hetil. 1997 Oct 12;138(41):2593-7.
6
[Endoscopic therapy of acute upper gastrointestinal bleeding. A breakthrough in non-variceal bleeding?].[急性上消化道出血的内镜治疗。非静脉曲张性出血的一项突破?]
Schweiz Med Wochenschr. 1988 Mar 19;118(11):393-7.
7
Endoscopic injection treatment in patients with shock and gastrointestinal bleeding or stigmata of recent hemorrhage.
Endoscopy. 1987 Sep;19(5):185-9. doi: 10.1055/s-2007-1018278.
8
[Possibilities and limits of endoscopic therapy in hemorrhage of the gastrointestinal tract].
Leber Magen Darm. 1987 Apr;17(2):69-79.
9
[Methods of injection in hemostasis of the gastrointestinal tract].[胃肠道止血的注射方法]
Z Gastroenterol. 1983 Jun;21(6):259-62.
10
[Endoscopic methods of non variceal upper gastrointestinal bleeding haemostasis--retrospective analysis].[非静脉曲张性上消化道出血内镜止血方法——回顾性分析]
Pol Merkur Lekarski. 2009 May;26(155):403-6.

引用本文的文献

1
Endoscopic injection therapy for bleeding peptic ulcer; a comparison of adrenaline alone with adrenaline plus ethanolamine oleate.内镜下注射治疗消化性溃疡出血;单用肾上腺素与肾上腺素加油酸乙醇胺的比较。
Gut. 1994 May;35(5):608-10. doi: 10.1136/gut.35.5.608.
2
Endoscopic intervention in bleeding peptic ulcer.内镜下治疗出血性消化性溃疡。
Gut. 1995 Aug;37(2):161-4. doi: 10.1136/gut.37.2.161.
3
Bleeding gastroduodenal ulcers: nonoperative treatment.胃十二指肠溃疡出血:非手术治疗
World J Surg. 1987 Jun;11(3):295-303. doi: 10.1007/BF01658106.
4
Endoscopic injection of adrenaline for actively bleeding ulcers: a randomised trial.内镜下注射肾上腺素治疗活动性出血性溃疡:一项随机试验。
Br Med J (Clin Res Ed). 1988 Jun 11;296(6637):1631-3. doi: 10.1136/bmj.296.6637.1631.
5
Heat probe thermocoagulation and pure alcohol injection in massive peptic ulcer haemorrhage: a prospective, randomised controlled trial.热探头热凝术与纯酒精注射治疗巨大消化性溃疡出血:一项前瞻性随机对照试验。
Gut. 1990 Jul;31(7):753-7. doi: 10.1136/gut.31.7.753.
6
Bleeding peptic ulcer--endoscopic and pharmacological management.出血性消化性溃疡——内镜及药物治疗
Postgrad Med J. 1991 Jul;67(789):606-12. doi: 10.1136/pgmj.67.789.606.
7
Management of upper gastrointestinal bleeding--the Prince of Wales Hospital experience.上消化道出血的管理——威尔士亲王医院的经验
Gastroenterol Jpn. 1991 Jul;26 Suppl 3:53-7. doi: 10.1007/BF02779263.
8
Endoscopic injection sclerotherapy in non-variceal upper gastrointestinal bleeding. A comparative study of polidocanol and thrombin.非静脉曲张性上消化道出血的内镜注射硬化疗法:聚多卡醇与凝血酶的对比研究
Surg Endosc. 1991;5(1):28-30. doi: 10.1007/BF00591383.
9
Endoscopic injection sclerosis: effective treatment for bleeding peptic ulcer.内镜注射硬化疗法:治疗消化性溃疡出血的有效方法。
Gut. 1991 Jul;32(7):727-9. doi: 10.1136/gut.32.7.727.
10
Endoscopic local injection of ethanolamine oleate and thrombin as an effective treatment for bleeding duodenal ulcer: a controlled trial.内镜下局部注射油酸乙醇胺和凝血酶治疗十二指肠溃疡出血的有效性:一项对照试验。
Gut. 1992 Apr;33(4):456-9. doi: 10.1136/gut.33.4.456.