Rösch J, Keller F S, Wawrukiewicz A S, Krippaehne W W, Dotter C T
Radiology. 1982 Dec;145(3):615-9. doi: 10.1148/radiology.145.3.6983087.
The source of recurrent massive lower gastrointestinal bleeding can sometimes escape detection by conventional diagnostic measures. In such situations, bleeding can be directly provoked by pharmacoangiography using vasodilators, anticoagulants, and/or fibrinolytic agents. Heparin, streptokinase, and tolazoline, used separately or in combination, can augment, prolong, or reactivate transient, covert bleeding, thereby facilitating angiographic identification and localization of the lesion. Physiological, clinical, and angiographic factors are discussed. Although rarely needed, this useful and sometimes crucial diagnostic approach demands the combined skills and support of the radiologist, clinician, and surgeon.
复发性大量下消化道出血的来源有时会逃过传统诊断方法的检测。在这种情况下，可通过使用血管扩张剂、抗凝剂和/或纤维蛋白溶解剂的药物血管造影直接诱发出血。单独或联合使用肝素、链激酶和妥拉唑啉，可增加、延长或重新激活短暂的隐匿性出血，从而便于血管造影识别和定位病变。文中讨论了生理、临床和血管造影因素。尽管很少需要，但这种有用且有时至关重要的诊断方法需要放射科医生、临床医生和外科医生的联合技能和支持。
