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刺激因子对亚致死剂量照射小鼠粒细胞生成的影响。

Effect of a stimulating factor on granulopoiesis in sublethally irradiated mice.

作者信息

Jovcić G, Stojanović N, Hajduković S

出版信息

Stem Cells (1981). 1982;1(4-5):233-9.

PMID:6983151
Abstract

Sublethally irradiated mice were used as a model for an in vivo study of the effect of the stimulating factor present in rat leukophoretic serum (LS). LS was obtained from rats with inflammation induced by polyvinylpyrrolidone. Irradiated mice were injected i.v. with 0.2 ml LS, normal rat serum or Parker 199 medium, respectively. Animals were sacrificed 24, 48 and 72 h later. The obtained data indicated that LS stimulated the proliferation of granulocytic cells in the period observed.

摘要

亚致死剂量照射的小鼠被用作体内研究大鼠白细胞分离血清(LS)中存在的刺激因子作用的模型。LS取自聚乙烯吡咯烷酮诱导炎症的大鼠。给照射后的小鼠分别静脉注射0.2 ml LS、正常大鼠血清或帕克199培养基。24、48和72小时后处死动物。所得数据表明,在观察期内LS刺激了粒细胞的增殖。

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