Von Boehmer H, Bennink J, Langhorne J
Eur J Immunol. 1982 Oct;12(10):892-5. doi: 10.1002/eji.1830121017.
The frequency of mutant-specific cytotoxic T lymphocyte precursors (CTL-P) has been analyzed in several mouse strains. While H-2 antigens of responder strains have a limited influence on the frequency of major H antigen-specific CTL-P, the frequency of mutant-specific CTL-P can be equally as high in unrelated and related strains. In general, the frequency does not reflect the closeness of kinship between stimulator and responder.
已在多种小鼠品系中分析了突变体特异性细胞毒性T淋巴细胞前体(CTL-P)的频率。虽然应答品系的H-2抗原对主要组织相容性复合体(MHC)抗原特异性CTL-P的频率影响有限,但在不相关和相关品系中,突变体特异性CTL-P的频率可能同样高。一般来说,该频率并不反映刺激细胞与应答细胞之间亲缘关系的紧密程度。