托美丁在正常及佐剂性关节炎Lewis大鼠体内的药代动力学及代谢情况 - Suppr

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超能文献

Pharmacokinetics and metabolism of tolmetin in normal and adjuvant arthritic Lewis rats.

作者信息

Grindel J M, Migdalof B H, Yorgey K A, Pritchard J F

出版信息

Eur J Drug Metab Pharmacokinet. 1982 Oct-Dec;7(4):299-306. doi: 10.1007/BF03189633.

DOI:10.1007/BF03189633

PMID:6984679

Abstract

摘要

相似文献

Pharmacokinetics and metabolism of tolmetin in normal and adjuvant arthritic Lewis rats.托美丁在正常及佐剂性关节炎Lewis大鼠体内的药代动力学及代谢情况

Eur J Drug Metab Pharmacokinet. 1982 Oct-Dec;7(4):299-306. doi: 10.1007/BF03189633.

Linear and nonlinear assessment of tolmetin pharmacokinetics.托美丁药代动力学的线性和非线性评估。

Res Commun Chem Pathol Pharmacol. 1977 Aug;17(4):583-93.

Absorption and excretion of tolemetin in man.托美丁在人体中的吸收与排泄。

Clin Pharmacol Ther. 1976 Feb;19(2):224-33. doi: 10.1002/cpt1976192224.

The pharmacokinetic and metabolic profile of the antiinflammatory agent tolmetin in laboratory animals and man.抗炎药托美丁在实验动物和人体中的药代动力学及代谢特征。

Drug Metab Rev. 1981;12(2):363-77. doi: 10.3109/03602538108994037.

Comparison of tolmetin kinetics in rheumatoid arthritis and matched healthy controls.类风湿关节炎患者与配对健康对照者中托美汀动力学的比较。

J Clin Pharmacol. 1983 Nov-Dec;23(11-12):557-62. doi: 10.1002/j.1552-4604.1983.tb01803.x.

Absorption and excretion of tolmetin in arthritic patients.托美丁在关节炎患者中的吸收与排泄

Clin Pharmacol Ther. 1979 Jul;26(1):122-8. doi: 10.1002/cpt1979261122.

Pharmacokinetics of tolmetin with and without concomitant administration of antacid in man.托美丁在人体中与抗酸剂联合或不联合给药时的药代动力学。

Eur J Clin Pharmacol. 1977 Dec 28;12(6):421-8. doi: 10.1007/BF00561061.

Tolmetin kinetics and synovial fluid prostaglandin E levels in rheumatoid arthritis.类风湿关节炎中托美丁的动力学及滑液中前列腺素E水平

Clin Pharmacol Ther. 1982 Sep;32(3):371-7. doi: 10.1038/clpt.1982.174.

[Pharmacokinetics of tolectin (tolmetin) in serum and in the synovial fluid].[血清及滑液中托美丁（痛灭定）的药代动力学]

Rev Esp Reum Enferm Osteoartic. 1980;23(2):153-6.

Lack of correlation between induction of adjuvant arthritis and changes in metabolism and disposition of phenylbutazone in rats.佐剂性关节炎的诱发与大鼠体内保泰松代谢及处置变化之间缺乏相关性。

Pharmacology. 1980;20(3):166-72. doi: 10.1159/000137361.

本文引用的文献

Pharmacologic evaluation of tolectin (tolmetin, mcn-2559) and mcn-2891, two anti-inflammatory agents.

J Pharmacol Exp Ther. 1973 Apr;185(1):127-38.

Impaired drug metabolism in rats with adjuvant-induced arthritis: a brief review.

Drug Metab Dispos. 1973 Jan-Feb;1(1):251-5.

Absorption and excretion of tolemetin in man.托美丁在人体中的吸收与排泄。

Clin Pharmacol Ther. 1976 Feb;19(2):224-33. doi: 10.1002/cpt1976192224.

Adjuvant-induced arthritis and drug-metabolizing enzymes.佐剂诱导性关节炎与药物代谢酶

Biochem Pharmacol. 1976 Dec 15;25(24):2683-8. doi: 10.1016/0006-2952(76)90257-4.

Protein binding of tolmetin.托美丁的蛋白结合率

Clin Pharmacol Ther. 1978 Dec;24(6):694-705. doi: 10.1002/cpt1978246694.

Biochem Pharmacol. 1978 May 1;27(9):1379-80. doi: 10.1016/0006-2952(78)90123-5.

Metabolism of tolmetin in rat, monkey, and man.托美丁在大鼠、猴和人体内的代谢。

Drug Metab Dispos. 1975 Jul-Aug;3(4):283-6.

Studies on disposition and metabolism of tolmetin, a new anti-inflammatory agent, in rats and mice. II. Urinary metabolites.新型抗炎药托美汀在大鼠和小鼠体内的处置与代谢研究。II. 尿代谢产物

Drug Metab Dispos. 1979 Jan-Feb;7(1):20-3.

Studies on disposition and metabolism of tolmetin, a new anti-inflammatory agent, in rats and mice. I. Absorption, distribution, and excrection of [14C]tolmetin radioactivity.新型抗炎药托美丁在大鼠和小鼠体内的处置与代谢研究。I. [¹⁴C]托美丁放射性的吸收、分布及排泄

Drug Metab Dispos. 1979 Jan-Feb;7(1):14-9.

The time course of tolmetin and its metabolites in the plasma of individual rats and mice.托美丁及其代谢产物在大鼠和小鼠个体血浆中的时间进程。

Drug Metab Dispos. 1976 Sep-Oct;4(5):468-73.

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