Mehtar S
Scott Med J. 1982;27 Spec No.:S24-7. doi: 10.1177/00369330820270S106.
Twenty-three patients were treated with Augmentin for severe respiratory tract infections caused by beta-lactamase producing organisms. The success rate, clinically and bacteriologically, was 19 out of 23. One non beta-lactamase producing H. influenzae, and three mixed organisms including Staph aureus accounted for the four failures. The elimination of the organisms, sensitive to Augmentin were quick and clinical improvement was seen in 72 hours. The only side effects noted were nausea in three patients, which abated on taking the tablets with meals. Augmentin is a useful drug in the treatment of respiratory tract infection particularly in acute exacerbation of chronic bronchitis.
23例由产β-内酰胺酶的微生物引起的严重呼吸道感染患者接受了阿莫西林克拉维酸钾治疗。临床和细菌学上的成功率为23例中的19例。4例治疗失败的病例中,1例为非产β-内酰胺酶的流感嗜血杆菌,3例为包括金黄色葡萄球菌在内的混合微生物感染。对阿莫西林克拉维酸钾敏感的微生物清除迅速,72小时内可见临床改善。仅观察到3例患者出现恶心的副作用,随餐服药后症状减轻。阿莫西林克拉维酸钾是治疗呼吸道感染的有效药物,尤其适用于慢性支气管炎急性加重期。