严重高血压和肾功能不全患者使用恩屈嗪的情况。
Endralazine in patients with severe hypertension and renal insufficiency.
作者信息
Higgs E R, Harrison P R, Banks R A, Kingswood J C, Mackenzie J C
出版信息
Postgrad Med J. 1982 Dec;58(686):767-70. doi: 10.1136/pgmj.58.686.767.
Endralazine, a new peripheral vasodilator, was given in conjunction with a beta-blocker to 21 patients with hypertension and chronic renal failure. All subjects were either poorly controlled on their previous antihypertensive regime or were experiencing unacceptable adverse effects from drugs. After 4 weeks blood pressure was reduced in all patients and symptomatic side effects were few. Two patients became anti-nuclear factor (ANF) positive in weak titre but without evidence of the lupus syndrome.
恩屈嗪是一种新型外周血管扩张剂，与β受体阻滞剂联合用于21例高血压合并慢性肾衰竭患者。所有受试者之前的抗高血压治疗方案效果不佳，或正在经历药物难以接受的不良反应。4周后，所有患者血压均降低，且症状性副作用较少。两名患者抗核因子（ANF）呈弱阳性，但无狼疮综合征证据。
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