前房内接种单纯疱疹病毒I型可诱导前房相关免疫偏离。
Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation.
作者信息
Whittum J A, Niederkorn J Y, McCulley J P, Streilein J W
出版信息
Curr Eye Res. 1982;2(10):691-7. doi: 10.3109/02713688209019998.
PMID:6985281
Abstract
Herpes simplex virus Type 1 (HSV-1) inoculated intracamerally (IC) into the anterior chamber of BALB/c eyes induces anterior chamber associated immune deviation (ACAID) in which T cell-mediated delayed type hypersensitivity (DTH) responses to HSV-1 are impaired while B cell-mediated anti-HSV neutralizing antibody responses are intact or enhanced.
摘要
将1型单纯疱疹病毒（HSV-1）经前房内（IC）接种到BALB/c小鼠眼中，可诱导前房相关免疫偏离（ACAID），其中对HSV-1的T细胞介导的迟发型超敏反应（DTH）受损，而B细胞介导的抗HSV中和抗体反应则保持完整或增强。
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