Chun C H, Raff M J, Contreras L, Varghese R, Waterman N, Daffner R, Melo J C
Medicine (Baltimore). 1980 Jan;59(1):50-65. doi: 10.1097/00005792-198001000-00003.
Fourteen cases of splenic abscess are reported and 159 cases previously cited in the literature are reviewed. The incidence, predisposing factors, pathogenesis, clinical features, bacteriology and radiologic findings are discussed. Infective endocarditis was the most common single antecedent infection. Hemoglobinopathies, non-penetrating abdominal trauma, and gastrointestinal malignancy appear to predispose the spleen to abscess formation. Emphasis is placed on clinical features and radiologic findings to aid practitioners in diagnosing this uncommon but often fatal infection. Also emphasized is the necessity for prompt surgical intervention when splenic abscess is suspected. An approach to the antimicrobial therapy in different clinical settings is outlined.
报告了14例脾脓肿病例，并对文献中先前引用的159例病例进行了回顾。讨论了发病率、易感因素、发病机制、临床特征、细菌学和影像学表现。感染性心内膜炎是最常见的单一前驱感染。血红蛋白病、非穿透性腹部创伤和胃肠道恶性肿瘤似乎使脾脏易形成脓肿。重点关注临床特征和影像学表现，以帮助医生诊断这种罕见但往往致命的感染。还强调了怀疑脾脓肿时及时进行手术干预的必要性。概述了在不同临床情况下的抗菌治疗方法。
