McLone D G
Childs Brain. 1980;6(2):65-73. doi: 10.1159/000119887.
Closure of a myelomeningocele should be based on an understanding of the altered anatomy. Reconstruction of the defect, including the form of the spinal cord, is dependent on this understanding. Assuming the exposed neural plaque is potentially functional tissue is the principle reason for preserving all neural tissue and for anatomical reconstruction of the spinal cord. Closure of the central canal of the spinal cord and suspension of neural tissue in a pia-arachnoid lined CSF compartment establishes a more normal microenvironment. It is hoped that this closure will prevent adhesion of neural elements to the closure and subsequent tethering of the spinal cord later in the child's life.
脊髓脊膜膨出的闭合应基于对改变的解剖结构的理解。缺损的重建,包括脊髓的形态,取决于这种理解。假定暴露的神经板是潜在的功能组织,是保留所有神经组织以及进行脊髓解剖重建的主要原因。闭合脊髓中央管并将神经组织悬吊于蛛网膜下腔衬里的脑脊液腔室中,可建立更正常的微环境。希望这种闭合能防止神经元件与闭合处粘连以及在儿童后期脊髓发生继发性栓系。