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釉原蛋白在下颌脊椎动物牙齿牙釉质中的免疫组织化学定位。

Immunohistochemical localization of amelogenins in enameloid of lower vertebrate teeth.

作者信息

Herold R C, Graver H T, Christner P

出版信息

Science. 1980 Mar 21;207(4437):1357-8. doi: 10.1126/science.6986656.

DOI:10.1126/science.6986656
PMID:6986656
Abstract

The indirect method of immunofluorescence was used to demonstrate the presence of amelogenins in the enameloid of teeth and dermal denticles of Chondrichthyes; in the enameloid of Teleostei and Amphibia; and in the enamel of Reptilia. Nonmammalian amelogenins are formed in the ectodermal cells of tooth organs and chemically are so similar to mammalian amelogenins that they interact with antiserum prepared from bovine enamel matrix.

摘要

采用间接免疫荧光法来证明牙釉蛋白存在于软骨鱼类牙齿的类釉质和真皮小齿中；硬骨鱼类和两栖类的类釉质中；以及爬行类的牙釉质中。非哺乳类动物的牙釉蛋白在牙齿器官的外胚层细胞中形成，并且在化学性质上与哺乳类动物的牙釉蛋白非常相似，以至于它们能与从牛牙釉质基质制备的抗血清发生相互作用。

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Immunohistochemical localization of amelogenins in enameloid of lower vertebrate teeth.釉原蛋白在下颌脊椎动物牙齿牙釉质中的免疫组织化学定位。
Science. 1980 Mar 21;207(4437):1357-8. doi: 10.1126/science.6986656.
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引用本文的文献

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Paleo-evo-devo implications of a revised conceptualization of enameloids and enamels.牙釉质和牙釉质修订概念化的古进化发育生物学意义
Biol Rev Camb Philos Soc. 2025 Jun;100(3):1047-1066. doi: 10.1111/brv.13173. Epub 2024 Dec 18.
2
Genetic basis for the evolution of vertebrate mineralized tissue.脊椎动物矿化组织进化的遗传基础。
Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11356-61. doi: 10.1073/pnas.0404279101. Epub 2004 Jul 22.
3
Immunohistochemical localisation of amelogenin-like proteins and type I collagen and histochemical demonstration of sulphated glycoconjugates in developing enameloid and enamel matrices of the larval urodele (Triturus pyrrhogaster) teeth.
幼体有尾目（日本林蛙）牙齿发育中的类釉原蛋白和I型胶原蛋白的免疫组织化学定位以及硫酸化糖缀合物的组织化学显示
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4
Construction and identification of mouse amelogenin cDNA clones.小鼠釉原蛋白cDNA克隆的构建与鉴定
Proc Natl Acad Sci U S A. 1983 Dec;80(23):7254-8. doi: 10.1073/pnas.80.23.7254.
5
The fine structure of initial mineralisation during tooth development in the gummy shark, Mustelus manazo, Elasmobranchia.姥鲨（皱唇鲨科，豹鲨属）牙齿发育过程中初始矿化的精细结构，板鳃亚纲。
J Anat. 1989 Jun;164:175-87.
6
Phylogenetic distribution of enamel proteins: immunohistochemical localization with monoclonal antibodies indicates the evolutionary appearance of enamelins prior to amelogenins.
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7
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Amelogenin gene similarity in vertebrates: DNA sequences encoding amelogenin seem to be conserved during evolution.脊椎动物中釉原蛋白基因的相似性：编码釉原蛋白的DNA序列在进化过程中似乎是保守的。
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Immunochemical and immunohistochemical studies, using antisera against porcine 25 kDa amelogenin, 89 kDa enamelin and the 13-17 kDa nonamelogenins, on immature enamel of the pig and rat.利用针对猪25 kDa釉原蛋白、89 kDa釉蛋白和13 - 17 kDa非釉原蛋白的抗血清，对猪和大鼠的未成熟牙釉质进行免疫化学和免疫组织化学研究。
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