Chan M K, Varghese Z, Fernando O N, Moorhead J F
Br Med J. 1980 Jan 19;280(6208):150-1. doi: 10.1136/bmj.280.6208.150.
The evolution of nocturnal polyuria and saluresis in renal allograft recipients was studied by comparing the day to night (D:N) ratios of urine volume and sodium excretion in 15 patients who had undergone transplantation less than one year previously (recent-transplant group) with those in 11 patients who had undergone transplantation at least one year previously. Eleven patients with chronic renal failure and 12 normal subjects served as controls. Patients in the recent-transplant group had significantly lower D:N ratios of urine volume and sodium excretion than the patients who had undergone transplantation at least a year before, while the ratios in this last group did not differ significantly from those in the normal subjects. Nocturnal polyuria and saluresis gradually subsided in five patients studied for three months. Chronic renal failure and uraemic autonomic neuropathy were unlikely causes of the nocturia. The patients in the recent-transplant group had significantly lower D:N ratios of urine volume than the controls with chronic renal failure, and the mean Valsalva ratio in eight of them was not significantly different from that in the normal subjects. An undue sensitivity of renal allografts to postural influences was proposed.
通过比较15例移植时间不到一年的患者（近期移植组）与11例移植时间至少一年的患者的尿量和钠排泄的昼夜（D:N）比值，研究了肾移植受者夜间多尿和盐利尿的演变。11例慢性肾衰竭患者和12例正常受试者作为对照。近期移植组患者的尿量和钠排泄的D:N比值显著低于移植至少一年的患者，而最后一组患者的比值与正常受试者的比值无显著差异。在研究的5例患者中，夜间多尿和盐利尿在三个月内逐渐消退。慢性肾衰竭和尿毒症自主神经病变不太可能是夜尿症的原因。近期移植组患者的尿量D:N比值显著低于慢性肾衰竭对照组，其中8例患者的平均瓦尔萨尔瓦比值与正常受试者的比值无显著差异。有人提出肾移植对体位影响过度敏感。
