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Effect of a single amino acid substitution on the near-ultraviolet CD spectra of tryptophan synthase alpha-subunit.

作者信息

Yutani K, Ogasahara K, Suzuki M, Sugino Y

出版信息

J Biochem. 1980 Jan;87(1):117-21. doi: 10.1093/oxfordjournals.jbchem.a132716.

DOI:10.1093/oxfordjournals.jbchem.a132716
PMID:6987209
Abstract
摘要

相似文献

1
Effect of a single amino acid substitution on the near-ultraviolet CD spectra of tryptophan synthase alpha-subunit.单个氨基酸取代对色氨酸合酶α亚基近紫外圆二色光谱的影响。
J Biochem. 1980 Jan;87(1):117-21. doi: 10.1093/oxfordjournals.jbchem.a132716.
2
Comparison of denaturation by guanidine hydrochloride of the wild type tryptophan synthase alpha-subunit of Escherichia coli and two mutant protein (Glu 49 replaced by Met or Gln).
J Biochem. 1979 Apr;85(4):915-21. doi: 10.1093/oxfordjournals.jbchem.a132423.
3
Evidence that glutamic acid 49 of tryptophan synthase alpha subunit is a catalytic residue. Inactive mutant proteins substituted at position 49 bind ligands and transmit ligand-dependent to the beta subunit.
J Biol Chem. 1988 Jun 25;263(18):8611-4.
4
Effects of the phenylalanine-22----leucine, glutamic acid-49----methionine, glycine-234----aspartic acid, and glycine-234----lysine mutations on the folding and stability of the alpha subunit of tryptophan synthase from Escherichia coli.
Biochemistry. 1986 May 20;25(10):2965-74. doi: 10.1021/bi00358a035.
5
Proton nuclear magnetic resonance studies on the wild-type and single amino acid substituted tryptophan synthase alpha-subunits.对野生型和单氨基酸取代的色氨酸合酶α亚基的质子核磁共振研究。
Biochemistry. 1987 Sep 8;26(18):5666-71. doi: 10.1021/bi00392a013.
6
Effect of single amino acid substitutions on the protease susceptibility of tryptophan synthase alpha subunit.
Eur J Biochem. 1985 Jul 1;150(1):17-21. doi: 10.1111/j.1432-1033.1985.tb08979.x.
7
pH dependence of stability of the wild-type tryptophan synthase alpha-subunit and two mutant proteins (Glu49 replaced by Met or Gln).野生型色氨酸合酶α亚基及两种突变蛋白（谷氨酸49被甲硫氨酸或谷氨酰胺取代）稳定性的pH依赖性
J Mol Biol. 1980 Dec 25;144(4):455-65. doi: 10.1016/0022-2836(80)90331-9.
8
Tryptophan synthase alpha subunit glutamic acid 49 is essential for activity. Studies with 19 mutants at position 49.色氨酸合酶α亚基的谷氨酸49对活性至关重要。对49位的19个突变体进行了研究。
J Biol Chem. 1987 Oct 5;262(28):13429-33.
9
Comparison of CD spectra in the aromatic region on a series of variant proteins substituted at a unique position of tryptophan synthase alpha-subunit.对一系列在色氨酸合酶α亚基独特位置进行取代的变体蛋白质在芳香族区域的圆二色光谱进行比较。
Proteins. 1989;5(3):211-7. doi: 10.1002/prot.340050304.
10
Synergism in folding of a double mutant of the alpha subunit of tryptophan synthase.色氨酸合酶α亚基双突变体折叠中的协同作用。
Biochemistry. 1986 Oct 21;25(21):6356-60. doi: 10.1021/bi00369a002.

引用本文的文献

1
Quantitative first principles calculations of protein circular dichroism in the near-ultraviolet.近紫外区蛋白质圆二色性的定量第一性原理计算
Chem Sci. 2017 Jun 1;8(6):4318-4333. doi: 10.1039/c7sc00586e. Epub 2017 Mar 24.
2
Effects of denaturing and stabilizing agents on the inhibitory activity and conformational stability of Schizolobium parahyba chymotrypsin inhibitor.变性剂和稳定剂对巴西裂榄糜蛋白酶抑制剂抑制活性和构象稳定性的影响。
J Protein Chem. 2000 Aug;19(6):507-13. doi: 10.1023/a:1026505616359.
3
Dependence of conformational stability on hydrophobicity of the amino acid residue in a series of variant proteins substituted at a unique position of tryptophan synthase alpha subunit.
在色氨酸合酶α亚基的一个独特位置被取代的一系列变体蛋白中，构象稳定性对氨基酸残基疏水性的依赖性。
Proc Natl Acad Sci U S A. 1987 Jul;84(13):4441-4. doi: 10.1073/pnas.84.13.4441.