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Regulation of leucine and alpha-ketoisocaproic acid metabolism in skeletal muscle. Effects of starvation and insulin.

作者信息

Hutson S M, Zapalowski C, Cree T C, Harper A E

出版信息

J Biol Chem. 1980 Mar 25;255(6):2418-26.

PMID:6987222
Abstract
摘要

相似文献

1
Regulation of leucine and alpha-ketoisocaproic acid metabolism in skeletal muscle. Effects of starvation and insulin.骨骼肌中亮氨酸和α-酮异己酸代谢的调节。饥饿和胰岛素的影响。
J Biol Chem. 1980 Mar 25;255(6):2418-26.
2
Regulation of leucine and alpha-ketoisocaproate metabolism in skeletal muscle.骨骼肌中亮氨酸和α-酮异己酸代谢的调节
J Biol Chem. 1978 Nov 25;253(22):8126-33.
3
Ketoisocaproic acid, a metabolite of leucine, suppresses insulin-stimulated glucose transport in skeletal muscle cells in a BCAT2-dependent manner.酮异己酸是亮氨酸的一种代谢产物，它以一种依赖于BCAT2的方式抑制胰岛素刺激的骨骼肌细胞中的葡萄糖转运。
Am J Physiol Cell Physiol. 2016 Sep 1;311(3):C518-27. doi: 10.1152/ajpcell.00062.2016. Epub 2016 Aug 3.
4
Fetal fuels. IV. Regulation of branched-chain amino and keto acid metabolism in fetal brain.胎儿营养物质。IV. 胎儿大脑中支链氨基酸和酮酸代谢的调节
Am J Physiol. 1981 Sep;241(3):E200-7. doi: 10.1152/ajpendo.1981.241.3.E200.
5
A paired-tracer dilution method for characterizing membrane transport in the perfused rat hindlimb. Effects of insulin, feeding and fasting on the kinetics of sugar transport.一种用于表征灌注大鼠后肢膜转运的双示踪剂稀释法。胰岛素、进食和禁食对糖转运动力学的影响。
Biochem J. 1983 Sep 15;214(3):737-43. doi: 10.1042/bj2140737.
6
Assessment of effect of starvation, glucose, fatty acids and hormones on alpha-decarboxylation of leucine in skeletal muscle of rat.饥饿、葡萄糖、脂肪酸及激素对大鼠骨骼肌中亮氨酸α-脱羧作用影响的评估。
J Nutr. 1976 Aug;106(8):1079-88. doi: 10.1093/jn/106.8.1079.
7
Fetal fuels VI. Metabolism of alpha-ketoisocaproic acid in fetal rat brain.胎儿营养物质VI. 胎鼠脑内α-酮异己酸的代谢
Metabolism. 1983 May;32(5):421-7. doi: 10.1016/0026-0495(83)90001-x.
8
Oxidation of branched chain amino acids by isolated hearts and diaphragms of the rat. The effect of fatty acids, glucose, and pyruvate respiration.大鼠离体心脏和膈肌对支链氨基酸的氧化作用。脂肪酸、葡萄糖和丙酮酸呼吸的影响。
J Biol Chem. 1972 Dec 25;247(24):8085-96.
9
Effects of perfusate leucine concentration on the metabolism of valine by the isolated rat hindquarter.灌注液亮氨酸浓度对离体大鼠后肢缬氨酸代谢的影响。
Metabolism. 1984 Oct;33(10):922-7. doi: 10.1016/0026-0495(84)90246-4.
10
Effects of insulin on whole body and forearm leucine and KIC metabolism in type 1 diabetes.胰岛素对1型糖尿病患者全身及前臂亮氨酸和α-酮异己酸代谢的影响。
Am J Physiol. 1990 Jul;259(1 Pt 1):E96-103. doi: 10.1152/ajpendo.1990.259.1.E96.

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Branched-Chain Amino Acids and Brain Metabolism.支链氨基酸与脑代谢
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2
Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond.T细胞活化中的亮氨酸代谢：mTOR信号通路及其他
Adv Nutr. 2016 Jul 15;7(4):798S-805S. doi: 10.3945/an.115.011221. Print 2016 Jul.
3
Sites of superoxide and hydrogen peroxide production by muscle mitochondria assessed ex vivo under conditions mimicking rest and exercise.在模拟休息和运动的条件下，对离体肌肉线粒体产生超氧化物和过氧化氢的位点进行评估。
J Biol Chem. 2015 Jan 2;290(1):209-27. doi: 10.1074/jbc.M114.619072. Epub 2014 Nov 11.
4
Lactating porcine mammary tissue catabolizes branched-chain amino acids for glutamine and aspartate synthesis.泌乳猪乳腺组织分解支链氨基酸以合成谷氨酰胺和天冬氨酸。
J Nutr. 2009 Aug;139(8):1502-9. doi: 10.3945/jn.109.105957. Epub 2009 Jun 23.
5
Leucine supplementation and intensive training.亮氨酸补充与强化训练。
Sports Med. 1999 Jun;27(6):347-58. doi: 10.2165/00007256-199927060-00001.
6
The regulation of branched-chain 2-oxo acid dehydrogenase of liver, kidney and heart by phosphorylation.肝脏、肾脏和心脏中支链2-氧代酸脱氢酶的磷酸化调节。
Biochem J. 1981 May 15;196(2):459-69. doi: 10.1042/bj1960459.
7
Effects of lactation on L-leucine metabolism in the rat. Studies in vivo and in vitro.哺乳期对大鼠L-亮氨酸代谢的影响。体内和体外研究。
Biochem J. 1981 Mar 15;194(3):941-7. doi: 10.1042/bj1940941.
8
The effect of starvation on branched-chain 2-oxo acid oxidation in rat muscle.饥饿对大鼠肌肉中支链2-氧代酸氧化的影响。
Biochem J. 1984 Apr 1;219(1):253-60. doi: 10.1042/bj2190253.
9
Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation.孵育过程中大鼠膈肌支链2-氧代酸脱氢酶活性状态增加及总活性丧失。
Biochem J. 1984 Dec 1;224(2):491-6. doi: 10.1042/bj2240491.
10
Metabolism of valine and 3-methyl-2-oxobutanoate by the isolated perfused rat kidney.缬氨酸和3-甲基-2-氧代丁酸在离体灌注大鼠肾脏中的代谢
Biochem J. 1984 Nov 15;224(1):109-16. doi: 10.1042/bj2240109.