Frame J W
J Oral Surg. 1980 Apr;38(4):251-6.
Implants of porous calcium sulphate dihydrate with a surface coating of n-butyl 2-cyanoacrylate were studied in circular defects in the skulls of rabbits to determine the extent of their replacement by new bone and to examine the reaction of the surrounding tissue. The defects were compared with control cavities that were allowed to fill with blood clot. The material was well tolerated by the tissues and did not slow bony healing. The pattern of ingrowth of bone in the skulls with implants was different than that of the controls. Further investigations are being undertaken to strengthen the implants and to adjust the rate of biodegradation. Possible future clinical applications are discussed.
对带有正丁基 2 - 氰基丙烯酸酯表面涂层的多孔二水硫酸钙植入物在兔颅骨圆形缺损处进行了研究，以确定新骨对其替代的程度，并检查周围组织的反应。将这些缺损与允许充满血凝块的对照腔进行比较。该材料在组织中耐受性良好，且未减缓骨愈合。植入物所在颅骨中骨长入的模式与对照不同。正在进行进一步研究以强化植入物并调整生物降解速率。还讨论了未来可能的临床应用。
