前列腺素I2（前列环素）。
Prostaglandin I2 (prostacyclin).
作者信息
Kelton J G, Blajchman M A
出版信息
Can Med Assoc J. 1980 Jan 26;122(2):175-9.
Abstract
Prostaglandin I2 (PGI2), or prostacyclin, is a recently discovered prostaglandin that affects many organ systems. It is both a potent inhibitor of platelet aggregation and a powerful vasodilator. The recent demonstration that it is the main prostaglandin synthesized by the blood vessel wall suggests that it may play an important role in limiting platelet-mediated thrombosis. However, despite considerable investigation, the exact physiological role of PGI2 has yet to be elucidated.
摘要
前列腺素I2（PGI2），即前列环素，是一种最近发现的影响多个器官系统的前列腺素。它既是血小板聚集的强效抑制剂，也是一种强大的血管扩张剂。最近的研究表明它是血管壁合成的主要前列腺素，这表明它可能在限制血小板介导的血栓形成中发挥重要作用。然而，尽管进行了大量研究，PGI2的确切生理作用仍有待阐明。
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The inhibition of platelet aggregation by an aorta intima extract.
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Stimulation of human platelet adenylate cyclase by prostaglandin D2.前列腺素D2对人血小板腺苷酸环化酶的刺激作用。
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Cultured human skin fibroblasts and arterial cells produce a labile platelet-inhibitory prostaglandin.培养的人皮肤成纤维细胞和动脉细胞会产生一种不稳定的血小板抑制性前列腺素。
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Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid.前列环素（PGX）是由花生四烯酸诱导冠状动脉舒张的内源性代谢产物。
Prostaglandins. 1977 Jan;13(1):3-15. doi: 10.1016/0090-6980(77)90037-5.
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Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides.动脉壁可通过一种由前列腺素内过氧化物生成的物质（前列腺素X）来防止血小板血栓的沉积。
Prostaglandins. 1976 Nov;12(5):685-713. doi: 10.1016/0090-6980(76)90047-2.
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An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation.从动脉中分离出的一种酶可将前列腺素内过氧化物转化为一种抑制血小板聚集的不稳定物质。
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Enhancement of platelet aggregation by tranylcypromine in mouse cerebral microvessels.
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