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瘢痕性类天疱疮或瘢痕性线状IgA大疱性皮肤病1例。

A case of cicatricial pemphigoid or cicatricial linear IgA bullous dermatosis.

作者信息

Kumar V, Rogozinski T, Yarbrough C, Beutner E H, Chorzelski T P

出版信息

J Am Acad Dermatol. 1980 Apr;2(4):327-31. doi: 10.1016/s0190-9622(80)80046-6.

Abstract

A case has been described with clinical features of cicatricial pemphigoid, but immunofluorescent (IF) biopsy findings are suggestive of linear IgA bullous dermatosis (LABD), i.e., the presence of IgA deposits with a linear pattern at the basement membrane zone. The patient failed to respond to sulfones and gave a limited response to corticosteroid. These findings suggest that therapy of the type found to be effective in cutaneous forms of LABD, i.e., combinations of low doses of sulfones and corticosteroids, may be indicated in such cases.

摘要

已描述了一例具有瘢痕性类天疱疮临床特征的病例,但免疫荧光(IF)活检结果提示为线性IgA大疱性皮肤病(LABD),即在基底膜带存在呈线性模式的IgA沉积。该患者对砜类药物无反应,对皮质类固醇反应有限。这些发现表明,对于此类病例,可能需要采用在LABD皮肤型中被发现有效的治疗方法,即低剂量砜类药物与皮质类固醇的联合使用。

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