Yow M D, Leeds L J, Thompson P K, Mason E O, Clark D J, Beachler C W
Am J Obstet Gynecol. 1980 May 1;137(1):34-8. doi: 10.1016/0002-9378(80)90382-8.
A longitudinal study of colonization by group B streptococcus (GBS) was conducted in 93 pregnant women and 92 of their infants. Positive cultures were obtained from vaginal swab specimens on at least one occasion during pregnancy from 20.4% of the women. Three types of carriage were observed: chronic, transient, and intermittent. At the time of delivery, 12.9% of the mothers were colonized by GBS. GBS colonization occurred in 41.7% of the infants of the mothers colonized intrapartum. Only 1.2% of infants intrapartum culture-negative mothers were colonized. Infants colonized at birth were culture negative by 4 months of age. This study suggests that interruption of vertical transmission of GBS from mother to infant not only would influence the incidence of early-onset GBS disease but also might reduce the incidence of late-onset GBS disease.
对93名孕妇及其92名婴儿进行了一项关于B族链球菌（GBS）定植的纵向研究。在孕期至少有一次从20.4%的女性阴道拭子标本中获得阳性培养物。观察到三种携带类型：慢性、短暂性和间歇性。分娩时，12.9%的母亲被GBS定植。在产时被GBS定植的母亲中，41.7%的婴儿发生了GBS定植。产时培养阴性母亲的婴儿中只有1.2%被定植。出生时被定植的婴儿在4个月大时培养转为阴性。这项研究表明，中断GBS从母亲到婴儿的垂直传播不仅会影响早发性GBS疾病的发病率，还可能降低晚发性GBS疾病的发病率。
