抗结核菌素抗血清对卡介苗感染豚鼠迟发型超敏反应的持久增强作用。
A long-lasting enhancing effect of anti-tuberculin antiserum on delayed-type hypersensitivity reaction in BCG-infected guinea pigs.
作者信息
Mauch H, Hammer H J, Kümel G
出版信息
Immunobiology. 1980 Jan;156(4-5):477-82. doi: 10.1016/S0171-2985(80)80081-7.
PMID:6989751
Abstract
Anti-tuberculin serum and anti-BCG immunoglobulins from immunized guinea pigs were transferred into recipient guinea pigs which had been infected with BCG. An enhancement of tuberculin skin reactivity was observed 7 and 35 days after transfer of homologous antiserum in comparison to a control group. This indicates a modulating effect of humoral factors, presumably specific antibodies on the expression of delayed-type hypersensitivity reaction after immunostimulation with BCG.
摘要
将来自免疫豚鼠的抗结核菌素血清和抗卡介苗免疫球蛋白转移至已感染卡介苗的受体豚鼠体内。与对照组相比，在转移同源抗血清7天和35天后观察到结核菌素皮肤反应性增强。这表明体液因子，可能是特异性抗体，对卡介苗免疫刺激后迟发型超敏反应的表达具有调节作用。
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