Martio J
Scand J Rheumatol. 1980;9(1):55-9. doi: 10.1080/03009748009098130.
46 patients who had an ulcer (verified by X-ray pictures) during treatment at the Rheumatism Foundation Hospital were compared with two patient groups of the same size. The first control group consisted of randomly selected patients who had been examined in the same way for the same indications but where the X-ray pictures did not show any ulcer. The subjects in the second control group were of the same age and sex as the ulcer patients; this control group did not undergo any X-ray examination and had no history of ulcer. The study revealed that although most rheumatic patients were women (as in the first control group) there were significantly more men among the ulcer patients. The use of rapidly dissolving acetylsalicylic acid tablets was more common in the ulcer group; correspondingly the slowly absorbed tablets were used significantly more often by the controls. The risk of ulcer was also increased by the simultaneous use of several anti-inflammatory analgesics and/or corticosteroids.
在风湿病基金会医院接受治疗期间出现溃疡（经X光片证实）的46名患者与两组规模相同的患者进行了比较。第一对照组由随机挑选的患者组成，这些患者因相同指征接受了相同方式的检查，但X光片未显示任何溃疡。第二对照组的受试者与溃疡患者年龄和性别相同；该对照组未接受任何X光检查且无溃疡病史。研究表明，尽管大多数风湿患者为女性（与第一对照组一样），但溃疡患者中的男性明显更多。溃疡组更常使用速溶阿司匹林片；相应地，对照组更常使用吸收缓慢的片剂。同时使用几种抗炎镇痛药和/或皮质类固醇也会增加溃疡风险。
