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Non-steroidal anti-inflammatory drugs in patients with peptic ulcer disease: rarely justified in terms of cost or patient benefit.消化性溃疡病患者使用非甾体抗炎药：从成本或患者获益角度来看，很少有合理性。
BMJ. 1989 Jan 21;298(6667):177-8. doi: 10.1136/bmj.298.6667.177.
2
Non-steroidal anti-inflammatory drugs in patients with peptic ulcer disease: to be considered in certain circumstances.消化性溃疡病患者使用非甾体抗炎药：在某些情况下需予以考虑。
BMJ. 1989 Jan 21;298(6667):176, 178-9. doi: 10.1136/bmj.298.6667.176.
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Aliment Pharmacol Ther. 1987;1 Suppl 1:540S-547S. doi: 10.1111/j.1365-2036.1987.tb00663.x.
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[New antirheumatism agents in old stomachs].
Ned Tijdschr Geneeskd. 1986 Oct 11;130(41):1827-9.
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Proton-pump inhibitors reduce the risk of uncomplicated peptic ulcer in elderly either acute or chronic users of aspirin/non-steroidal anti-inflammatory drugs.质子泵抑制剂可降低阿司匹林/非甾体抗炎药的老年急性或慢性使用者发生单纯性消化性溃疡的风险。
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The epidemiology of NSAID associated gastrointestinal disease.
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Misoprostol/NSAID fixed combinations. Help or hindrance in clinical practice?米索前列醇/非甾体抗炎药固定复方制剂。对临床实践是助力还是阻碍？
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Economic evaluation of gastric ulcer prophylaxis in patients with arthritis receiving non-steroidal anti-inflammatory drugs.对接受非甾体抗炎药治疗的关节炎患者进行胃溃疡预防的经济学评估。
Postgrad Med J. 1990 Aug;66(778):639-46. doi: 10.1136/pgmj.66.778.639.

本文引用的文献

1
Absorption of drugs from the stomach. II. The human.药物从胃中的吸收。II. 人体。
J Pharmacol Exp Ther. 1957 Aug;120(4):540-5.
2
Resistance to medical therapy of gastric ulcers in rheumatic disease patients taking aspirin. A double-blind study with cimetidine and follow-up.服用阿司匹林的风湿性疾病患者胃溃疡的药物治疗抵抗。西咪替丁双盲研究及随访。
Dig Dis Sci. 1982 Nov;27(11):976-80. doi: 10.1007/BF01391742.
3
Bleeding from peptic ulcers and use of non-steroidal anti-inflammatory drugs in the Romford area.罗姆福德地区消化性溃疡出血及非甾体抗炎药的使用情况
Br Med J (Clin Res Ed). 1985 Dec 7;291(6509):1609-10. doi: 10.1136/bmj.291.6509.1609.
4
Clinical pharmacology of platelet cyclooxygenase inhibition.血小板环氧化酶抑制的临床药理学
Circulation. 1985 Dec;72(6):1177-84. doi: 10.1161/01.cir.72.6.1177.
5
Non-steroidal anti-inflammatory drugs and life threatening complications of peptic ulceration.非甾体抗炎药与消化性溃疡的危及生命并发症
Gut. 1987 May;28(5):527-32. doi: 10.1136/gut.28.5.527.
6
Randomised study of the influence of non-steroidal anti-inflammatory drugs on the treatment of peptic ulcer in patients with rheumatic disease.非甾体抗炎药对风湿性疾病患者消化性溃疡治疗影响的随机研究。
Gut. 1987 Feb;28(2):226-9. doi: 10.1136/gut.28.2.226.
7
Cimetidine therapy in nonsteroidal anti-inflammatory drug gastropathy. Double-blind long-term evaluation.西咪替丁治疗非甾体抗炎药所致胃病。双盲长期评估。
Arch Intern Med. 1987 Oct;147(10):1798-801.
8
Prevention of gastroduodenal damage induced by non-steroidal anti-inflammatory drugs: controlled trial of ranitidine.预防非甾体抗炎药所致胃十二指肠损伤：雷尼替丁对照试验
BMJ. 1988 Oct 22;297(6655):1017-21. doi: 10.1136/bmj.297.6655.1017.
9
Ulcerogenicity of piroxicam: an analysis of spontaneously reported data.吡罗昔康的致溃疡作用：对自发报告数据的分析
Br Med J (Clin Res Ed). 1987 Jan 17;294(6565):147-50. doi: 10.1136/bmj.294.6565.147.
10
The protective effects of sulphasalazine against ethanol-induced gastric damage in rats.柳氮磺胺吡啶对大鼠乙醇诱导的胃损伤的保护作用。
Br J Pharmacol. 1987 Sep;92(1):31-7. doi: 10.1111/j.1476-5381.1987.tb11292.x.

Non-steroidal anti-inflammatory drugs in patients with peptic ulcer disease: rarely justified in terms of cost or patient benefit.

作者信息

Hawkey C

机构信息

Department of Therapeutics, University Hospital, Nottingham.

出版信息

BMJ. 1989 Jan 21;298(6667):177-8. doi: 10.1136/bmj.298.6667.177.

DOI:10.1136/bmj.298.6667.177
PMID:2493845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1835449/
Abstract
摘要