Evaluation of glycopyrrolate and atropine as adjuncts to reversal of non-depolarizing neuromuscular blocking agents in a "true-to-life" situation.
作者信息
Cozanitis D A, Dundee J W, Merrett J D, Jones C J, Mirakhur R K
出版信息
Br J Anaesth. 1980 Jan;52(1):85-9. doi: 10.1093/bja/52.1.85.
PMID:6990948
Abstract
Glycopyrrolate, a quaternary ammonium anticholinergic compound, and atropine were evaluated in combination with neostigmine for antagonism of non-depolarizing neuromuscular block. A total of 641 patients were investigated in a "true-to-life" situation. The patients receiving glycopyrrolate with neostigmine had smaller changes in heart rate than those who received atropine. This was particularly apparent in patients with cardiovascular disease.
摘要
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