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蕈样肉芽肿的组织学、电子光学及组织化学研究结果

[Histological, electron-optical and histochemical findings in mycosis fungoides].

作者信息

Stanová M, Elleder M, Hrochová L, Vosmik F, Komárek J

出版信息

Cesk Patol. 1978 May;14(2):79-84.

PMID:699109
Abstract

Skin excisions were investigated in 5 patients with verified mycosis fungoides. Findings yielded by light and electron microscopy helped to confirm the findings anticipated, and were correlated with histochemical observations. One of the cases involved a substantially higher activity of lysosomal enzymes, particularly KF and beta-glucuronidase in the skin infiltrate mycotic cells. In the other cases, this sort of activity was low. The significance of high ATPase activity in the peripheral cell membrane remains unclear. In one case, involvement in the T lymphocyte series was confirmed by the formation of rosettes.

摘要

对5例经证实的蕈样肉芽肿患者进行了皮肤切除术。光镜和电镜检查结果有助于证实预期的发现,并与组织化学观察结果相关联。其中1例患者皮肤浸润性真菌细胞中的溶酶体酶,特别是KF和β-葡萄糖醛酸酶活性显著较高。在其他病例中,这种活性较低。外周细胞膜中高ATP酶活性的意义尚不清楚。在1例病例中,通过玫瑰花结的形成证实了T淋巴细胞系列的受累。

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