• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

英国对沙利度胺所致肢体缺陷儿童的治疗回顾。

Review of the treatment of thalidomide children with limb defeciency in Great Britain.

作者信息

Fletcher I

出版信息

Clin Orthop Relat Res. 1980 May(148):18-25.

PMID:6991189
Abstract

Thalidomide-induced deformities, affecting some 400 British children, caused various combinations of malformations. Classified by type of defect and whether confined to upper and/or lower limbs, the malformations can be treated on a radional basis. The treatment from infancy to the present time includes the fitting of carbon dioxide gas-powered upper limb prostheses, initially in their simplest form and finally in the most sophisticated form. For a baby with bilateral lower phocomelia, a special "sitting socket" was devised to enable sitting in an upright position. When each child was about 12 to 15 months of age, extension protheses were supplied and the effects on walking when upper limbs are malformed or absent were noted. The methods of achieving personal independence and developing constructive youngests' pastimes are important. One patient was so well rehabilitated that she was able to marry and start a healthy family.

摘要

沙利度胺导致的畸形影响了约400名英国儿童,造成了各种畸形组合。根据缺陷类型以及是否仅限于上肢和/或下肢进行分类,这些畸形可以在常规基础上进行治疗。从婴儿期至今的治疗包括安装以二氧化碳气体为动力的上肢假肢,最初是最简单的形式,最终是最复杂的形式。对于患有双侧下肢短肢畸形的婴儿,设计了一种特殊的“坐姿承窝”,以便能坐直。当每个孩子大约12至15个月大时,提供伸展假肢,并记录上肢畸形或缺失时对行走的影响。实现个人独立和培养有建设性的青少年消遣方式很重要。有一名患者康复得非常好,以至于能够结婚并组建一个健康的家庭。

相似文献

1
Review of the treatment of thalidomide children with limb defeciency in Great Britain.英国对沙利度胺所致肢体缺陷儿童的治疗回顾。
Clin Orthop Relat Res. 1980 May(148):18-25.
2
[Reductional anomalies of the limbs].
LARC Med. 1982 Dec;2(11):968-77.
3
Habilitation of patients with congenital malformations associated with thalidomide: surgery of limb defects.沙利度胺相关先天性畸形患者的康复治疗:肢体缺陷手术
Can Med Assoc J. 1963 May 11;88(19):964-72.
4
The acceptance and rejection of prostheses by children with multiple congenital limb deformities.患有多发性先天性肢体畸形的儿童对假肢的接受与排斥情况。
Artif Limbs. 1968 Spring;12(1):1-13.
5
Swivel walkers. Experiences in fitting swivel walkers to children with severe lower-limb deformities.旋转助行器。为重度下肢畸形儿童适配旋转助行器的经验。
Ann Phys Med. 1969 Aug;10(3):106-11.
6
[Documentation and report on thalidomide damage].[关于沙利度胺损害的文件记录与报告]
Z Orthop Ihre Grenzgeb. 1973 Feb;111(1):93-103.
7
[The medical examination of children with malformations suspected to be due to thalidomide].
Lakartidningen. 1969 Oct 29;66(44):4539-47 passim.
8
The thalidomide syndrome: risks of exposure and spectrum of malformations.
Clin Perinatol. 1986 Sep;13(3):555-73.
9
[Congenital malformations in the past 10 years: incidence of aplasias of the extremities, with special reference to the so-called thalidomide embryopathy].[过去10年的先天性畸形:肢体发育不全的发病率,特别提及所谓的沙利度胺胚胎病]
Ann Sanita Pubblica. 1967 Sep-Oct;28(5):1269-319.
10
Appendicular skeletal and visceral malformations induced by thalidomide in bonnet monkeys.
Teratology. 1973 Apr;7(2):151-9. doi: 10.1002/tera.1420070206.

引用本文的文献

1
Secondary musculoskeletal disability and rehabilitation aspects in adults with thalidomide embryopathy: A narrative review.沙利度胺胚胎病成人患者的继发性肌肉骨骼残疾及康复问题:一项叙述性综述
Intractable Rare Dis Res. 2025 Aug 31;14(3):175-182. doi: 10.5582/irdr.2025.01032.
2
PROTACs: A novel strategy for cancer drug discovery and development.PROTACs:癌症药物发现与开发的新策略。
MedComm (2020). 2023 May 29;4(3):e290. doi: 10.1002/mco2.290. eCollection 2023 Jun.
3
Drug Repurposing for Cancer Therapy.用于癌症治疗的药物重新利用。
J Cancer Sci Ther. 2012 Jul 21;4(7):ix-xi. doi: 10.4172/1948-5956.1000e108.