• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Scope and limitations of experimental chemotherapy.

作者信息

Zak O

出版信息

Experientia. 1980 Apr 15;36(4):479-83. doi: 10.1007/BF01975159.

DOI:10.1007/BF01975159
PMID:6991272
Abstract
摘要

相似文献

1
Scope and limitations of experimental chemotherapy.实验性化疗的范围与局限性
Experientia. 1980 Apr 15;36(4):479-83. doi: 10.1007/BF01975159.
2
Prediction of peak penicillin and cephalosporin concentrations in canine serum as derived from in vitro serum and tissue quantitative protein binding.
J Antimicrob Chemother. 1979 Mar;5(2):219-27. doi: 10.1093/jac/5.2.219.
3
Binding rate of antibacterials to serum proteins.
J Pharm Sci. 1977 Nov;66(11):1663-4. doi: 10.1002/jps.2600661150.
4
Evaluation of the effect of serum proteins on the antibacterial activity and pharmacodynamics of ceftaroline against Staphylococcus aureus.评估血清蛋白对头孢洛林抗金黄色葡萄球菌抗菌活性及药效学的影响。
Int J Antimicrob Agents. 2013 Sep;42(3):285-7. doi: 10.1016/j.ijantimicag.2013.05.015. Epub 2013 Jul 26.
5
Physiological perfusion model for cephalosporin antibiotics I: Model selection based on blood drug concentrations.头孢菌素类抗生素的生理灌注模型I:基于血药浓度的模型选择
J Pharm Sci. 1978 Feb;67(2):191-6. doi: 10.1002/jps.2600670217.
6
Prediction of plasma protein binding of cephalosporins using an artificial neural network.使用人工神经网络预测头孢菌素的血浆蛋白结合率
Pharmazie. 2007 Feb;62(2):157-8.
7
Studies on protein binding of cefazolin and other antibiotics.头孢唑林及其他抗生素的蛋白结合研究。
Jpn J Antibiot. 1974 Jun;27(3):296-301.
8
The importance of target validation in drug discovery and development.靶点验证在药物发现与开发中的重要性。
Curr Opin Drug Discov Devel. 2009 Sep;12(5):581-4.
9
Removal of cephalosporins by continuous arteriovenous ultrafiltration (CAVU) and hemofiltration (CAVH).通过持续动静脉超滤(CAVU)和血液滤过(CAVH)清除头孢菌素。
Int J Artif Organs. 1989 Jun;12(6):379-83.
10
Blood levels and tissue concentrations of cefazedone in animals.
Arzneimittelforschung. 1979;29(2a):400-3.

引用本文的文献

1
Non invasive real-time monitoring of bacterial infection & therapeutic effect of anti-microbials in five mouse models.五种小鼠模型中细菌感染和抗菌药物治疗效果的非侵入性实时监测。
Indian J Med Res. 2011 Nov;134(5):688-95. doi: 10.4103/0971-5916.90997.
2
The granuloma pouch: an in vivo model for pharmacokinetic and chemotherapeutic investigations. II. Microbiological characterization.肉芽肿袋:用于药代动力学和化疗研究的体内模型。II. 微生物学特征
Infection. 1983 Jan-Feb;11(1):41-6. doi: 10.1007/BF01651357.
3
Animal models as predictors of the safety and efficacy of antibiotics.

本文引用的文献

1
A simplified method of evaluating dose-effect experiments.一种评估剂量效应实验的简化方法。
J Pharmacol Exp Ther. 1949 Jun;96(2):99-113.
2
Virulence to mice of Staphylococcus pyogenes: its measurement and its relation to certain in vitro properties.化脓性链球菌对小鼠的毒力:其测定及其与某些体外特性的关系。
Br J Exp Pathol. 1952 Aug;33(4):315-26.
3
[Experimental vaginal candidiasis of the rat].
Pathol Microbiol (Basel). 1960;23:62-8.
作为抗生素安全性和有效性预测指标的动物模型。
Eur J Clin Microbiol Infect Dis. 1990 Jul;9(7):472-8. doi: 10.1007/BF01964286.
4
Animal models in the evaluation of antimicrobial agents.抗菌药物评价中的动物模型。
Antimicrob Agents Chemother. 1991 Aug;35(8):1527-31. doi: 10.1128/AAC.35.8.1527.
5
Evaluation of quinolones in experimental animal models of infections.喹诺酮类药物在感染实验动物模型中的评估。
Eur J Clin Microbiol Infect Dis. 1991 Apr;10(4):275-90. doi: 10.1007/BF01967001.
4
A consideration of the pathogenesis of bacterial meningitis: review of experimental and clinical studies.细菌性脑膜炎发病机制的思考:实验与临床研究综述
Yale J Biol Med. 1960 Feb;32(4):280-309.
5
EXPERIMENTAL PYELONEPHRITIS. ASCENDING INFECTION OF THE RAT KIDNEY BY ORGANISMS RESIDING IN THE URETHRA.实验性肾盂肾炎。尿道内细菌上行感染大鼠肾脏
Br J Exp Pathol. 1964 Aug;45(4):436-41.
6
[Microbial persistence studied in vivo by employment of artificial fibrin coagulate. I. Growth of bacteria in fibrin coagulate. Streptococcus viridans persistence after penicillin administration].[通过使用人工纤维蛋白凝块在体内研究微生物持续性。I. 细菌在纤维蛋白凝块中的生长。青霉素给药后绿色链球菌的持续性]
Klin Wochenschr. 1960 Jun 1;38:521-8. doi: 10.1007/BF01482680.
7
Guide to antibiotic therapy of experimental bacterial infections in mice.小鼠实验性细菌感染的抗生素治疗指南。
J Bacteriol. 1961 Feb;81(2):233-5. doi: 10.1128/jb.81.2.233-235.1961.
8
Experimental pyelonephritis. IV. Observations on infections resulting from direct inoculation of bacteria in different zones of the kidney.实验性肾盂肾炎。IV. 关于细菌直接接种于肾脏不同区域所导致感染的观察
Yale J Biol Med. 1958 Jun;30(6):406-14.
9
Significance and utilization of animal individuality in disease research.动物个体差异在疾病研究中的意义与应用
J Natl Cancer Inst. 1954 Dec;15(3):555-70; discussion, 571-2.
10
Chemotherapeutic activity of rifampin against gram-negative bacteria with reference to urinary-tract infection in rats.利福平对革兰氏阴性菌的化疗活性及其与大鼠尿路感染的关系。
Antimicrob Agents Chemother (Bethesda). 1968;8:519-23.