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在对转录因子σ温度敏感的大肠杆菌突变体限制过程中核糖核酸聚合酶合成的调控

Regulation of ribonucleic acid polymerase synthesis during restriction of an Escherichia coli mutant temperature sensitive for transcription factor sigma.

作者信息

Blumenthal R M, Dennis P P

出版信息

J Bacteriol. 1980 Jun;142(3):1049-54. doi: 10.1128/jb.142.3.1049-1054.1980.

DOI:10.1128/jb.142.3.1049-1054.1980
PMID:6991491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC294139/
Abstract

An Escherichia coli mutant temperature sensitive for the sigma subunit of ribonucleic acid polymerase was shifted to restrictive temperatures. In response to these restrictions the transcription of rpoBC increased markedly, and the synthesis rates of the beta and beta' subunits of ribonucleic acid polymerase increased. The ratio of the beta and beta' synthesis rates (beta/beta') decreased.

摘要

一株对核糖核酸聚合酶的σ亚基温度敏感的大肠杆菌突变体被转移至限制温度下。作为对这些限制条件的响应，rpoBC的转录显著增加，并且核糖核酸聚合酶的β亚基和β'亚基的合成速率增加。β亚基与β'亚基的合成速率之比（β/β'）下降。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a1/294139/69b4b7fb5f70/jbacter00567-0316-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a1/294139/69b4b7fb5f70/jbacter00567-0316-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a1/294139/69b4b7fb5f70/jbacter00567-0316-a.jpg

相似文献

1
Regulation of ribonucleic acid polymerase synthesis during restriction of an Escherichia coli mutant temperature sensitive for transcription factor sigma.在对转录因子σ温度敏感的大肠杆菌突变体限制过程中核糖核酸聚合酶合成的调控
J Bacteriol. 1980 Jun;142(3):1049-54. doi: 10.1128/jb.142.3.1049-1054.1980.
2
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Proc Natl Acad Sci U S A. 1978 Dec;75(12):6177-81. doi: 10.1073/pnas.75.12.6177.
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引用本文的文献

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Evidence that rifampicin can stimulate readthrough of transcriptional terminators in Escherichia coli, including the attenuator of the rpoBC operon.有证据表明利福平可刺激大肠杆菌中转录终止子的通读，包括rpoBC操纵子的弱化子。
Nucleic Acids Res. 1982 Nov 25;10(22):7409-24. doi: 10.1093/nar/10.22.7409.
2
Isolation of a recombinant lambda phage carrying nusA and surrounding region of the Escherichia coli K-12 chromosome.携带大肠杆菌K-12染色体nusA及其周边区域的重组λ噬菌体的分离。
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3
Direct evidence for autogenous regulation of the Escherichia coli genes rpoBC in vivo.

本文引用的文献

1
Evidence for specific control of RNA polymerase synthesis in Escherichia coli.大肠杆菌中RNA聚合酶合成特异性调控的证据。
Nat New Biol. 1973 May 2;243(122):6-9.
2
Regulation of RNA polymerase synthesis. Conditional lethal amber mutations in the beta subunit gene.RNA聚合酶合成的调控。β亚基基因中的条件致死性琥珀突变。
J Biol Chem. 1980 Apr 25;255(8):3536-41.
3
Gene expression in Escherichia coli after amino acid, purine, or pyrimidine exhaustion.氨基酸、嘌呤或嘧啶耗尽后大肠杆菌中的基因表达。
大肠杆菌基因rpoBC在体内进行自体调节的直接证据。
Mol Gen Genet. 1986 Mar;202(3):500-8. doi: 10.1007/BF00333284.
4
Direct evidence for rifampicin-promoted readthrough of the partial terminator tL7 in the rpoBC operon of Escherichia coli.利福平促进大肠杆菌rpoBC操纵子中部分终止子tL7通读的直接证据。
Mol Gen Genet. 1987 Dec;210(2):358-63. doi: 10.1007/BF00325706.
5
Evidence that Rho and NusA are involved in termination in the rplL-rpoB intercistronic region.有证据表明Rho和NusA参与rplL-rpoB基因间区域的终止过程。
J Bacteriol. 1987 May;169(5):2277-80. doi: 10.1128/jb.169.5.2277-2280.1987.
6
Transcription frequency modulates the efficiency of an attenuator preceding the rpoBC RNA polymerase genes of Escherichia coli: possible autogenous control.转录频率调节大肠杆菌RNA聚合酶基因rpoBC之前的弱化子的效率：可能的自体调控。
Nucleic Acids Res. 1992 Sep 25;20(18):4773-9. doi: 10.1093/nar/20.18.4773.
J Bacteriol. 1980 Apr;142(1):202-11. doi: 10.1128/jb.142.1.202-211.1980.
4
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
Nature. 1970 Aug 15;227(5259):680-5. doi: 10.1038/227680a0.
5
The selectivity of transcription.转录的选择性
Annu Rev Biochem. 1974;43(0):721-75. doi: 10.1146/annurev.bi.43.070174.003445.
6
Regulation of ribonucleic acid synthesis in Escherichia coli B-r: an analysis of a shift-up. II. Fraction of RNA polymerase engaged in the synthesis of stable RNA at different steady-state growth rates.大肠杆菌B-r中核糖核酸合成的调控：一次阶跃上调的分析。II. 在不同稳态生长速率下参与稳定RNA合成的RNA聚合酶的比例。
J Mol Biol. 1973 Mar 25;75(1):161-79. doi: 10.1016/0022-2836(73)90536-6.
7
Identification of a gene for the alpha-subunit of RNA polymerase at the str-spc region of the Escherichia coli chromosome.在大肠杆菌染色体的str-spc区域鉴定RNA聚合酶α亚基的基因。
Proc Natl Acad Sci U S A. 1975 Dec;72(12):5036-40. doi: 10.1073/pnas.72.12.5036.
8
Regulation of the expression of ribosomal protein genes in Escherichia coli.大肠杆菌中核糖体蛋白基因表达的调控
J Mol Biol. 1975 Sep 5;97(1):61-76. doi: 10.1016/s0022-2836(75)80022-2.
9
Organization of ribosomal protein genes in Escherichia coli. I. Physical structure of DNA from transducing lambda phages carrying genes from the aroE-str region.大肠杆菌核糖体蛋白基因的组织。I. 携带来自aroE-str区域基因的转导λ噬菌体DNA的物理结构。
J Mol Biol. 1976 Sep 25;106(3):817-35. doi: 10.1016/0022-2836(76)90267-9.
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The relationship between function and DNA sequence in an intercistronic regulatory region in phage lambda.
Nature. 1978 Mar 30;272(5652):414-23. doi: 10.1038/272414a0.