Bell W R
Johns Hopkins Med J. 1980 Jun;146(6):289-99.
Disseminated intravascular coagulation (DIC) is a clinico-pathological syndrome of variable expression, resulting from uncontrolled simultaneous activation of the coagulation and fibrinolytic systems. DIC can be initiated in a variety of different ways. Additional studies are needed to determine the importance of vascular endothelial damage, hemodynamic alterations and the role of naturally occurring inhibitors of hemostasis. Progressive increase in our understanding of the mechanisms involved in triggering DIC will improve our therapeutic measures in the rational management of these patients. Absolutely essential in the successful management of patients with DIC is identification and control of the underlying illness.
弥散性血管内凝血（DIC）是一种临床表现多样的临床病理综合征，由凝血和纤溶系统同时不受控制地激活所致。DIC可通过多种不同方式引发。需要进一步研究以确定血管内皮损伤、血流动力学改变以及天然存在的止血抑制剂的作用的重要性。对引发DIC的相关机制的理解不断深入，将改善我们对这些患者进行合理管理的治疗措施。成功管理DIC患者的绝对必要条件是识别并控制潜在疾病。
