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[胰岛素依赖型患者的胎儿胰腺植入。技术与临床结果(作者译)]

[Foetal pancreas implants in an insulin-dependent patient. Technique and clinical results (author's transl)].

作者信息

Chastan P, Berjon J J, Gomez H, Meunier J M, Doutre L P

出版信息

Nouv Presse Med. 1980 Feb 2;9(6):353-4.

PMID:6992108
Abstract

Fragments of foetal pancreatic buds taken before the 10th week of gestation, stored at - 196 degrees C and cultivated on artificial media were implanted in an adult, insulin-dependent diabetic patient. Following a 2 weeks latent period, the clinical symptoms of diabetes regressed within 2 months, although all insulin treatment had been withdrawn. These results have now been maintained for 11 months, but major overloads in carbohydrates are imperfectly controlled.

摘要

取自妊娠10周前的胎儿胰腺芽碎片,保存在-196摄氏度并在人工培养基上培养后,被植入一名成年胰岛素依赖型糖尿病患者体内。经过2周的潜伏期后,糖尿病的临床症状在2个月内消退,尽管所有胰岛素治疗都已停止。这些结果现已维持了11个月,但碳水化合物的大量摄入仍控制得不够理想。

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