Slama G, Klein J C, Tardieu M C, Tchobroutsky G
Nouv Presse Med. 1977 Jun 25;6(26):2309-13.
Seven insulin-dependent diabetic were treated for 24 to 36 hours by intravenous injections of insulin adapted to variations in blood glucose using a fairly voluminous automatic regulation device. This artificial pancreas consists of a modified Technicon blood sugar apparatus which provides continuous estimation of blood glucose using non-haemolysed whole blood by a glucose oxidase method with an inertia time of 6 minutes, a table calculator and a newly developed interpretation and command electronic unit (GlucostatR). Normalisation of blood glucose was obtained for at least 24 hours, during and between meals, during a period following an oral glucose load and throughout the night.
七名胰岛素依赖型糖尿病患者使用相当庞大的自动调节装置，通过静脉注射根据血糖变化调整剂量的胰岛素进行了24至36小时的治疗。这种人工胰腺由一台改良的Technicon血糖分析仪组成，该分析仪采用葡萄糖氧化酶法，利用非溶血全血连续估算血糖，惯性时间为6分钟，还有一台台式计算器以及一个新开发的解读与指令电子单元（GlucostatR）。在进餐期间、餐间、口服葡萄糖负荷后的一段时间以及整个夜间，血糖至少在24小时内实现了正常化。
