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[使用非小型化人工胰腺使血糖正常化。7名胰岛素依赖型糖尿病患者24小时的应用(作者译)]

[The normalisation of blood sugar using a non-miniaturised artifical pancreas. Application for 24 hours in 7 insulin-dependent diabetics (author's transl)].

作者信息

Slama G, Klein J C, Tardieu M C, Tchobroutsky G

出版信息

Nouv Presse Med. 1977 Jun 25;6(26):2309-13.

PMID:887415
Abstract

Seven insulin-dependent diabetic were treated for 24 to 36 hours by intravenous injections of insulin adapted to variations in blood glucose using a fairly voluminous automatic regulation device. This artificial pancreas consists of a modified Technicon blood sugar apparatus which provides continuous estimation of blood glucose using non-haemolysed whole blood by a glucose oxidase method with an inertia time of 6 minutes, a table calculator and a newly developed interpretation and command electronic unit (GlucostatR). Normalisation of blood glucose was obtained for at least 24 hours, during and between meals, during a period following an oral glucose load and throughout the night.

摘要

七名胰岛素依赖型糖尿病患者使用相当庞大的自动调节装置,通过静脉注射根据血糖变化调整剂量的胰岛素进行了24至36小时的治疗。这种人工胰腺由一台改良的Technicon血糖分析仪组成,该分析仪采用葡萄糖氧化酶法,利用非溶血全血连续估算血糖,惯性时间为6分钟,还有一台台式计算器以及一个新开发的解读与指令电子单元(GlucostatR)。在进餐期间、餐间、口服葡萄糖负荷后的一段时间以及整个夜间,血糖至少在24小时内实现了正常化。

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