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[儿童反流性食管炎治疗的当前趋势]

[Current trends in the treatment of reflux esophagitis in childhood].

作者信息

Cirino E, Bianca T, Palomba R, Fusto A

出版信息

Chir Ital. 1978 Oct;30(5):543-54.

PMID:699226
Abstract

A problem of some complexity is the management of pathological gastro-esophageal reflux due to the presence of cardio-hiatal malformation, malposition of the cardia and gastric tuberosity, a congenitally short esophagus, and the like. Sometimes, however, there is no demonstrable morphological aleration and the condition, characterized by primitive hypotonia of the LES, goes under the name of infant chalasia of the esophagus. The general policy is to try first a conservative treatment consisting of dietary and postural measures and the administration of metoclopramide and d;ugs that protect the esophageal mucosa; this stage, however, should not be prolonged beyond 6 weeks. The presence of gastro-esophageal reflux associated with hiatal hernia; the presence of severe esophagitis or peptic stenosis of the esophagus and the persistence of symptoms after an adequate period of conservative therapy constitute as many indications for surgical correction. Good results can be obtained by restoring or strengthening the failing function of the LES, as is done quite successfully with funduplication after Nissen or with method of Belsey-Mark IV.

摘要

一个具有一定复杂性的问题是因贲门裂孔畸形、贲门和胃结节位置异常、先天性食管过短等导致的病理性胃食管反流的管理。然而,有时并无明显的形态学改变,这种以食管下括约肌原发性张力减退为特征的病症被称为婴儿食管失弛缓症。一般的策略是首先尝试保守治疗,包括饮食和体位措施以及给予甲氧氯普胺和保护食管黏膜的药物;然而,这个阶段不应超过6周。与食管裂孔疝相关的胃食管反流的存在;严重食管炎或食管消化性狭窄的存在以及在足够长的保守治疗期后症状持续存在,这些都构成了手术矫正的诸多指征。通过恢复或增强食管下括约肌衰退的功能可以取得良好效果,就像尼森胃底折叠术或贝尔西 - 马克IV法那样成功实施。

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