Michel J, Bercovici B, Sacks T
Surg Gynecol Obstet. 1980 Jul;151(1):55-7.
The antibacterial activity of peritoneal fluid obtained from 28 women undergoing laparoscopy was compared with that of ascitic fluid obtained from 11 patients with various pathologic conditions. Similar antibacterial activity was found in these two types of fluid. The activity varied from bactericidal to bacteriostatic and was directed mainly against gram-negative bacilli-Escherichia coli, Proteus mirabilis and Bacteroides fragilis. Candida albicans was inhibited by many of the fluids, but the activity against gram-positive cocci was much less marked. Lysozyme was present in the fluids but was not solely responsible for the antimicrobial activity. The results of this study suggest the presence of at least three groups of thermostable antibacterial substances, two of which are bactericidal and one, bacteriostatic. One of the bactericidal factors is complement-dependent.
对28名接受腹腔镜检查的女性的腹膜液抗菌活性与11名患有各种病理状况的患者的腹水抗菌活性进行了比较。在这两种类型的液体中发现了相似的抗菌活性。该活性从杀菌到抑菌不等，主要针对革兰氏阴性杆菌——大肠杆菌、奇异变形杆菌和脆弱拟杆菌。许多液体可抑制白色念珠菌，但对革兰氏阳性球菌的活性则不那么明显。液体中存在溶菌酶，但它并非抗菌活性的唯一原因。本研究结果表明存在至少三组热稳定抗菌物质，其中两组具有杀菌作用，一组具有抑菌作用。其中一种杀菌因子依赖补体。
