Fredriksson T, Lassus A, Bleeker J
Br J Dermatol. 1980 May;102(5):575-7. doi: 10.1111/j.1365-2133.1980.tb07658.x.
In a double-blind multi-centre study, comprising ninety-five patients with psoriasis and atopic dermatitis, 0.1% halcinonide cream applied once daily was equally as effective as the cream applied three times daily. However, the onset of action was more rapid when the cream was applied three times daily. In a control study once daily application of 0.1% halcinonide cream was found to be superior to the vehicle alone in the treatment of forty patients with the same diseases.
在一项双盲多中心研究中,95名银屑病和特应性皮炎患者参与其中,每日涂抹一次0.1%哈西奈德乳膏与每日涂抹三次的疗效相当。然而,每日涂抹三次时起效更快。在一项对照研究中,发现每日涂抹一次0.1%哈西奈德乳膏在治疗40名患有相同疾病的患者时优于单独使用赋形剂。