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新型胎盘蛋白和妊娠蛋白作为肿瘤学中可能的标志物。

New placental and pregnancy proteins as possible markers in oncology.

作者信息

Bohn H

出版信息

Klin Wochenschr. 1980 May 16;58(10):489-92. doi: 10.1007/BF01477065.

Abstract

A number of placental and pregnancy proteins has been detected by immunochemical methods in extracts from human term placentae. Several of these proteins already have been isolated and characterized and are now investigated for their usefulness as markers in oncology. Several of these proteins so long tested appear to be useful as markers in monitoring tumour patients, i.e. in the early detection of tumour recurrence or metastases and in the control of therapy. In addition, we hope that a combination of several of these new markers with already established tumour markers will enable to better diagnose tumours. Also will the use of solitary tissue proteins aid in the differential diagnosis of cancers.

摘要

通过免疫化学方法已在足月人胎盘提取物中检测到多种胎盘和妊娠蛋白。其中几种蛋白质已被分离和鉴定,目前正在研究它们作为肿瘤学标志物的用途。长期以来测试的其中几种蛋白质似乎可用作监测肿瘤患者的标志物,即在肿瘤复发或转移的早期检测以及治疗控制方面。此外,我们希望这些新标志物中的几种与已确立的肿瘤标志物相结合将能够更好地诊断肿瘤。单独的组织蛋白的使用也将有助于癌症的鉴别诊断。

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